ICOSLG Protein (AA 19-258) (His tag)
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- 抗原 See all ICOSLG 蛋白
- ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 19-258
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ICOSLG protein is labelled with His tag.
- 序列
- AA 19-258
- 产品特性
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.5 kDa. The protein migrates as 35-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product ICOSLG 蛋白
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Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 19-258) protein (His-Avi Tag)
ICOSLG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 19-258) protein (Fc Tag)ICOSLG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) protein (His-Avi Tag,Biotin)ICOSLG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 47-279) protein (His tag)ICOSLG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 19-256) protein (His tag)ICOSLG 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 18-135) protein (His-DYKDDDDK-Strep II Tag)ICOSLG 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 18-256) protein (His-DYKDDDDK-Strep II Tag)ICOSLG 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) protein (mFc-His Tag)ICOSLG 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. FACS
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 20-302) protein (GST tag)ICOSLG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (Active) protein (His tag,Fc Tag)ICOSLG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- 抗原
- ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
- 别名
- B7-H2 (ICOSLG 产品)
- 别名
- ICOSLG Protein, AU044799 Protein, B7-H2 Protein, B7RP-1 Protein, B7h Protein, BG071784 Protein, GI50 Protein, GL50 Protein, GL50-B Protein, ICOS-L Protein, Icoslg Protein, LICOS Protein, Ly115l Protein, mKIAA0653 Protein, B7H2 Protein, B7RP1 Protein, CD275 Protein, ICOSL Protein, Icosl Protein, RGD1562791 Protein, inducible T-cell costimulator ligand Protein, icos ligand Protein, inducible T-cell co-stimulator ligand Protein, ICOSLG Protein, Icosl Protein, Icoslg Protein
- 背景
- ICOS ligand (ICOSLG) is also known as B7 homolog 2 (B7-H2), B7-related protein 1 (B7RP-1) and CD antigen CD275, which belongs to the immunoglobulin superfamily and BTN/MOG family. ICOSLG contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. Isoform 1 is widely expressed, while isoform 2 is detected only in lymph nodes, leukocytes and spleen. B7-H2 is ligand for the T-cell-specific cell surface receptor ICOS. B7-H2 acts as a costimulatory signal for T-cell proliferation and cytokine secretion and induces also B-cell proliferation and differentiation into plasma cells. B7-H2 could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
- 分子量
- 27.8 kDa
- NCBI登录号
- NP_056074
- 途径
- Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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