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EGFR Protein (AA 25-647) (His tag)
EGFR
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
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EGFR
(Epidermal Growth Factor Receptor (EGFR))
蛋白类型
Recombinant
产品特性
AA 25-647
宿主
All origins for EGFR 蛋白
小鼠
资源
All sources for EGFR 蛋白
HEK-293 Cells
标记
This EGFR protein is labelled with His tag.
序列
AA 25-647
产品特性
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 70.1 kDa. The protein migrates as 110-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
纯度
>95 % as determined by SDS-PAGE.
过滤
0.22 μm filtered
内毒素水平
Less than 1.0 EU per μg by the LAL method.
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使用细节
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仅限研究用
贮存及处理
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状态
Lyophilized
缓冲液
PBS, pH 7.4
注意事项
Please avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
目标详细情况
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抗原
EGFR
(Epidermal Growth Factor Receptor (EGFR))
别名
EGF R (EGFR 产品 )
别名
C-erb Protein, CG10079 Protein, D-EGFR Protein, D-Egf Protein, DEGFR Protein, DER Protein, DER flb Protein, DER/EGFR Protein, DER/faint little ball Protein, DER/top Protein, DER/torpedo Protein, DER1 Protein, DEgfr Protein, Degfr Protein, Der Protein, DmHD-33 Protein, Dmel\\CG10079 Protein, EFG-R Protein, EGF-R Protein, EGFR Protein, EGFr Protein, EGfr Protein, EK2-6 Protein, Egf Protein, Egf-r Protein, EgfR Protein, El Protein, Elp Protein, Elp-1 Protein, Elp-B1 Protein, Elp-B1RB1 Protein, HD-33 Protein, TOP Protein, Torpedo/DER Protein, Torpedo/Egfr Protein, c-erbB Protein, d-egf-r Protein, dEGFR Protein, dEGFR1 Protein, dEgfr Protein, der Protein, egfr Protein, flb Protein, l(2)05351 Protein, l(2)09261 Protein, l(2)57DEFa Protein, l(2)57EFa Protein, l(2)57Ea Protein, mor1 Protein, top Protein, top/DER Protein, top/flb Protein, torpedo/Egfr Protein, torpedo/egfr Protein, EGFR12 Protein, EGFR15 Protein, egfr1 Protein, Erbb2 Protein, ERBB Protein, ERBB1 Protein, HER1 Protein, PIG61 Protein, mENA Protein, ErbB-1 Protein, Errp Protein, 9030024J15Rik Protein, AI552599 Protein, Erbb Protein, Errb1 Protein, Wa5 Protein, wa-2 Protein, wa2 Protein, epidermal growth factor receptor Protein, Epidermal growth factor receptor Protein, epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) Protein, EGFR Protein, Egfr Protein, egfra Protein, egfr1 Protein, LOC5564544 Protein
背景
The epidermal growth factor receptor (EGFR, ErbB-1, HER1) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.
分子量
71.2 kDa
NCBI登录号
NP_997538
途径
NF-kappaB Signaling , RTK signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Stem Cell Maintenance , Hepatitis C , Positive Regulation of Response to DNA Damage Stimulus , Interaction of EGFR with phospholipase C-gamma , Thromboxane A2 Receptor Signaling , EGFR Downregulation , S100 Proteins
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EGFR 蛋白
EGFR Protein (AA 25-647) (His tag) (ABIN2181005)