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CD5 Protein (CD5) (AA 25-372) (His tag)

CD5 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN2180809
发货至: 中国
  • 抗原 See all CD5 蛋白
    CD5
    蛋白类型
    Recombinant
    产品特性
    AA 25-372
    宿主
    • 19
    • 8
    • 4
    • 2
    • 1
    资源
    • 20
    • 5
    • 3
    • 3
    • 2
    • 1
    HEK-293 Cells
    标记
    This CD5 protein is labelled with His tag.
    序列
    AA 25-372
    产品特性
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 40.5 kDa. The protein migrates as 48-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CD5 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • 抗原
    CD5
    别名
    CD5 (CD5 产品)
    别名
    CD5 Protein, Ly-1 Protein, Ly-12 Protein, Ly-A Protein, Lyt-1 Protein, LEU1 Protein, T1 Protein, CD5 molecule Protein, CD5 antigen Protein, CD5 molecule like Protein, Cd5 molecule Protein, CD5 Protein, Cd5 Protein, CD5L Protein
    背景
    T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development,selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules.
    分子量
    40.5 kDa
    NCBI登录号
    NP_055022
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