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CD3D Protein (AA 22-105) (His tag)

CD3D 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
产品编号 ABIN2180772
发货至: 中国
  • 抗原 See all CD3D 蛋白
    CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
    蛋白类型
    Recombinant
    产品特性
    AA 22-105
    宿主
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    资源
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    HEK-293 Cells
    标记
    This CD3D protein is labelled with His tag.
    序列
    AA 22-105
    产品特性
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 11 kDa. The protein migrates as 18-25 kDa under reducing (R) condition (SDS-PAGE).
    纯度
    >90 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CD3D 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • 抗原
    CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
    别名
    CD3 delta (CD3D 产品)
    别名
    CD3-DELTA Protein, T3D Protein, CD3 Protein, T3d Protein, CD3d molecule Protein, CD3 antigen, delta polypeptide Protein, CD3D Protein, Cd3d Protein
    背景
    CD3D is also known as CD3-DELTA, T3D, and is a single-pass type I membrane protein. CD3D is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. Defects in CD3D cause severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T-/B+/NK+ SCID) which is a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels.
    分子量
    11.4 kDa
    NCBI登录号
    NP_000723
    途径
    TCR Signaling, CXCR4-mediated Signaling Events
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