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C5A Protein (AA 679-751)

C5a 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN2180666
发货至: 中国
  • 抗原 See all C5A (C5a) 蛋白
    C5A (C5a) (Complement Component 5a (C5a))
    蛋白类型
    Recombinant
    产品特性
    AA 679-751
    宿主
    • 5
    • 4
    • 4
    • 2
    • 2
    资源
    • 15
    • 1
    大肠杆菌(E. Coli)
    序列
    AA 679-751
    产品特性
    This protein carries no "tag". The protein has a calculated MW of 8.3 kDa. The protein migrates as 8.3 kDa under reducing (R) condition (SDS-PAGE).
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product C5a 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • 抗原
    C5A (C5a) (Complement Component 5a (C5a))
    别名
    Complement Component C5a (C5a 产品)
    别名
    C5a Protein, C5b Protein, CPAMD4 Protein, Hc Protein, RGD1561905 Protein, complement C5 Protein, C5 Protein
    背景
    Human Complement Component C5a (C5a) is also known as C5,and is a protein fragment released from complement component C5.,is a potent chemotactic factor for human peripheral blood neutrophils and monocytes, and is believed to play an important role in a number of inflammatory conditions. There are several functions in the below: C5a is an anaphylatoxin, causing the release of histamine from mast cells, C5a is effective leukocyte chemoattractants, causing the accumulation of white blood cells, especially neutrophil granulocytes, at sites of complement activation, C5a activates white blood cells by increasing avidity for white blood cell integrins and upregulating the Lipoxygenase pathway for arachidonic acid metabolism, C5a is a powerful inflammatory mediator, and seems to be a key factor in the development of pathology of many inflammatory diseases involving the complement system, C5a modulates balance between activating versus inhibitory IgG Fc receptors on leukocytes, thereby enhancing autoimmune response.
    分子量
    8.3 kDa
    UniProt
    P01031
    途径
    Complement System, Carbohydrate Homeostasis
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