Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (AA 1-339), (Extracellular Domain) (Active) protein (His tag)

ABIN2003167 产品详细信息, 供应商: Log in to see
蛋白名称
  • CX3CL1
  • DKFZp459K117
  • Cx3c
  • Scyd1
  • ABCD-3
  • C3Xkine
  • CXC3
  • CXC3C
  • NTN
  • NTT
  • SCYD1
  • fractalkine
  • neurotactin
  • AB030188
  • AI848747
  • CX3C
  • Cxc3
  • D8Bwg0439e
  • C-X3-C motif chemokine ligand 1
  • chemokine (C-X3-C motif) ligand 1
  • CX3CL1
  • Cx3cl1
产品特性
Extracellular Domain, AA 1-339
7
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
宿主

45
12
10
3
2
资源
人细胞
51
4
4
4
4
3
2
1
蛋白类型
Recombinant
生物活性
Active
标记
This CX3CL1 protein is labelled with His tag.
应用范围
Functional Studies (Func), SDS-PAGE (SDS)
选项
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产品特性 The secreted recombinant human CX3CL1 comprises 329 amino acids with a predicted molecular mass of 35 kDa. As a result of different glycosylation, rhCX3CL1 migrates between 50-70 kDa in SDS-PAGE under reducing conditions.

Protein Structure: A DNA sequence encoding the human CX3CL1 (NP_002987.1) extracellular domain (Met 1-Arg 339) with a C-terminal polyhistidine tag was expressed.
Predicted N-Term: Gln 25
纯度 > 95 % as determined by SDS-PAGE
内毒素水平 < 1.0 EU per μg of the protein as determined by the LAL method
Biological Activity Comment Measured by its ability to compete with biotinylated recombinant human CX3CL1-His for binding to immobilized recombinant mouse CD4-his in a functional ELISA.
背景 Synonyms: ABCD-3,C3Xkine,CXC3,CXC3C,fractalkine,neurotactin,NTN,NTT,SCYD1
分子量 35 kDa, 50-70 kDa
NCBI登录号 NP_002987
途径 Synaptic Membrane
应用备注 Optimal working dilution should be determined by the investigator.
限制 仅限研究用
状态 Lyophilized
缓冲液 Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
注意事项 Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
储存条件 -20 °C,-80 °C
储存方法 Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
有效期 12 months
厂商提供的图像
 image for Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (AA 1-339), (Extracellular Domain) (Active) protein (His tag) (ABIN2003167) Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (AA 1-339), (Extracellular Domain) (Active) protein (His tag)
有引用在: Wang, Hong, Huang, Jiang, Tao, Tan, Lu, Wang, Ahmed, Lu, Liu, Shi, Lai, Wilcox, Han: "P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy." in: Cell research, Vol. 25, Issue 6, pp. 674-90, 2015 (PubMed).

背景 Bazan, Bacon, Hardiman, Wang, Soo, Rossi, Greaves, Zlotnik, Schall: "A new class of membrane-bound chemokine with a CX3C motif." in: Nature, Vol. 385, Issue 6617, pp. 640-4, 1997 (PubMed).

Imai, Hieshima, Haskell, Baba, Nagira, Nishimura, Kakizaki, Takagi, Nomiyama, Schall, Yoshie: "Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion." in: Cell, Vol. 91, Issue 4, pp. 521-30, 1997 (PubMed).

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