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WASP Protein (AA 1-502) (GST tag)

WAS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
产品编号 ABIN1989806
发货至: 中国
  • 抗原 See all WASP (WAS) 蛋白
    WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
    蛋白类型
    Recombinant
    产品特性
    AA 1-502
    宿主
    • 4
    • 1
    资源
    • 2
    • 1
    • 1
    • 1
    小麦胚
    标记
    This WASP protein is labelled with GST tag.
    应用范围
    Western Blotting (WB), ELISA, Antibody Array (AA), Affinity Purification (AP)
    原理
    WAS (Human) Recombinant Protein (P01)
    序列
    MSGGPMGGRP GGRGAPAVQQ NIPSTLLQDH ENQRLFEMLG RKCLTLATAV VQLYLALPPG AEHWTKEHCG AVCFVKDNPQ KSYFIRLYGL QAGRLLWEQE LYSQLVYSTP TPFFHTFAGD DCQAGLNFAD EDEAQAFRAL VQEKIQKRNQ RQSGDRRQLP PPPTPANEER RGGLPPLPLH PGGDQGGPPV GPLSLGLATV DIQNPDITSS RYRGLPAPGP SPADKKRSGK KKISKADIGA PSGFKHVSHV GWDPQNGFDV NNLDPDLRSL FSRAGISEAQ LTDAETSKLI YDFIEDQGGL EAVRQEMRRQ EPLPPPPPPS RGGNQLPRPP IVGGNKGRSG PLPPVPLGIA PPPPTPRGPP PPGRGGPPPP PPPATGRSGP LPPPPPGAGG PPMPPPPPPP PPPPSSGNGP APPPLPPALV PAGGLAPGGG RGALLDQIRQ GIQLNKTPGA PESSALQPPP QSSEGLVGAL MHVMQKRSRA IHSSDEGEDQ AGDEDEDDEW DD
    产品特性
    Human WAS full-length ORF (AAH12738.1, 1 a.a. - 502 a.a.) recombinant protein with GST tag at N-terminal.
    纯化方法
    in vitro wheat germ expression system
    Top Product
    Discover our top product WAS 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -80 °C
    储存方法
    Best use within three months from the date of receipt of this protein.
  • 抗原
    WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
    别名
    WAS (WAS 产品)
    别名
    IMD2 Protein, SCNX Protein, THC Protein, THC1 Protein, WASP Protein, U42471 Protein, WASp Protein, Wasp Protein, imd2 Protein, thc Protein, thc1 Protein, was Protein, wasp Protein, wu:fk81c08 Protein, zgc:64164 Protein, Wiskott-Aldrich syndrome Protein, neural Wiskott-Aldrich syndrome protein Protein, wiskott-aldrich syndrome protein Protein, Wiskott-Aldrich syndrome L homeolog Protein, Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b Protein, WAS Protein, LOC5578888 Protein, CpipJ_CPIJ006699 Protein, Was Protein, was.L Protein, wasb Protein
    背景
    Synonyms: IMD2,THC,WASP
    Gene Description: Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
    Gene Name: WAS
    Gene Summary: The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.
    GenBank: BC012738.2, AAH12738.1
    分子量
    81.62 kDa (theoreatical)
    基因ID
    7454
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