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PFKFB1 Protein (AA 2-471) (His tag)

PFKFB1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1945453
发货至: 中国
  • 抗原 See all PFKFB1 蛋白
    PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
    蛋白类型
    Recombinant
    产品特性
    AA 2-471
    宿主
    • 7
    • 1
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    • 1
    资源
    • 2
    • 2
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    人细胞
    标记
    This PFKFB1 protein is labelled with His tag.
    原理
    Recombinant Human Fructose-2,6-Bisphosphatase 1/PFKFB1/PFK/FBPase 1 (C-6His)
    序列
    SPEMGELTQT RLQKIWIPHS SGSSRLQRRR GSSIPQFTNS PTMVIMVGLP ARGKTYISTK LTRYLNWIGT PTKVFNLGQY RREAVSYKNY EFFLPDNMEA LQIRKQCALA ALKDVHNYLS HEEGHVAVFD ATNTTRERRS LILQFAKEHG YKVFFIESIC NDPGIIAENI RQVKLGSPDY IDCDREKVLE DFLKRIECYE VNYQPLDEEL DSHLSYIKIF DVGTRYMVNR VQDHIQSRTV YYLMNIHVTP RSIYLCRHGE SELNIRGRIG GDSGLSVRGK QYAYALANFI QSQGISSLKV WTSHMKRTIQ TAEALGVPYE QWKALNEIDA GVCEEMTYEE IQEHYPEEFA LRDQDKYRYR YPKGESYEDL VQRLEPVIME LERQENVLVI CHQAVMRCLL AYFLDKSSDE LPYLKCPLHT VLKLTPVAYG CKVESIYLNV EAVNTHREKP ENVDITREPE EALDTVPAHY VDHHHHHH
    产品特性
    Recombinant Human PFKFB1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (AA 2-471) of Human PFKFB1 fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product PFKFB1 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    -80 °C
    储存方法
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
    别名
    PFKFB1 (PFKFB1 产品)
    别名
    zgc:55328 Protein, wu:fi11h10 Protein, PFKFB1 Protein, F6PK Protein, HL2K Protein, PFRX Protein, Pfkfb01 Protein, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Protein, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 S homeolog Protein, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 Protein, pfkfb1 Protein, PFKFB1 Protein, pfkfb1.S Protein, LOC100475853 Protein, Pfkfb1 Protein
    背景
    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
    分子量
    55.6 kDa
    UniProt
    P16118
    途径
    Regulation of Carbohydrate Metabolic Process
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