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CFHR5 Protein (AA 19-569) (His tag)

CFHR5 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1880676
发货至: 中国
  • 抗原 See all CFHR5 蛋白
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    蛋白类型
    Recombinant
    产品特性
    AA 19-569
    宿主
    资源
    • 1
    • 1
    • 1
    • 1
    • 1
    人细胞
    标记
    This CFHR5 protein is labelled with His tag.
    原理
    Recombinant Human Complement Factor H-related 5/CFHR5 (C-6His)
    序列
    EGTLCDFPKI HHGFLYDEED YNPFSQVPTG EVFYYSCEYN FVSPSKSFWT RITCTEEGWS PTPKCLRMCS FPFVKNGHSE SSGLIHLEGD TVQIICNTGY SLQNNEKNIS CVERGWSTPP ICSFTKGECH VPILEANVDA QPKKESYKVG DVLKFSCRKN LIRVGSDSVQ CYQFGWSPNF PTCKGQVRSC GPPPQLSNGE VKEIRKEEYG HNEVVEYDCN PNFIINGPKK IQCVDGEWTT LPTCVEQVKT CGYIPELEYG YVQPSVPPYQ HGVSVEVNCR NEYAMIGNNM ITCINGIWTE LPMCVATHQL KRCKIAGVNI KTLLKLSGKE FNHNSRIRYR CSDIFRYRHS VCINGKWNPE VDCTEKREQF CPPPPQIPNA QNMTTTVNYQ DGEKVAVLCK ENYLLPEAKE IVCKDGRWQS LPRCVESTAY CGPPPSINNG DTTSFPLSVY PPGSTVTYRC QSFYKLQGSV TVTCRNKQWS EPPRCLDPCV VSEENMNKNN IQLKWRNDGK LYAKTGDAVE FQCKFPHKAM ISSPPFRAIC QEGKFEYPIC EVDHHHHHH
    产品特性
    Recombinant Human Complement Factor H-related 5/CFHR5 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu19-Glu569) of Human CFHR5 fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CFHR5 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    别名
    Complement Factor H-Related 5/CFHR5 (CFHR5 产品)
    别名
    CFHL5 Protein, CFHR5D Protein, FHR-5 Protein, FHR5 Protein, complement factor H related 5 Protein, CFHR5 Protein
    Sub Type
    Fusionprotein
    背景
    Complement factor H-related protein 5(FHR-5 for short), is a secreted protein which contains 9 Sushi (CCP/SCR) domains. It is expressed by the liver and secreted in plasma. The pattern of the deposits is similar to other complement components, suggesting that FHR-5 may play a role in complement activation and regulation. Defects in CFHR5 have been found in patients with atypical hemolytic uremic syndrome and may contribute to the disease. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease.
    Alternative Names:
    分子量
    63.5 kDa
    UniProt
    Q9BXR6
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