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TNFRSF21 Protein (AA 42-350) (Fc Tag)

TNFRSF21 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1692269
发货至: 中国
  • 抗原 See all TNFRSF21 蛋白
    TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
    蛋白类型
    Recombinant
    产品特性
    AA 42-350
    宿主
    • 24
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    • 1
    资源
    • 10
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    人细胞
    标记
    This TNFRSF21 protein is labelled with Fc Tag.
    原理
    Recombinant Human Death Receptor 6/DR6/TNFRSF21/CD358 (C-Fc)
    序列
    QPEQKASNLI GTYRHVDRAT GQVLTCDKCP AGTYVSEHCT NTSLRVCSSC PVGTFTRHEN GIEKCHDCSQ PCPWPMIEKL PCAALTDREC TCPPGMFQSN ATCAPHTVCP VGWGVRKKGT ETEDVRCKQC ARGTFSDVPS SVMKCKAYTD CLSQNLVVIK PGTKETDNVC GTLPSFSSST SPSPGTAIFP RPEHMETHEV PSSTYVPKGM NSTESNSSAS VRPKVLSSIQ EGTVPDNTSS ARGKEDVNKT LPNLQVVNHQ QGPHHRHILK LLPSMEATGG EKSSTPIKGP KRGHPRQNLH KHFDINEHLV DDIEGRMDEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSREE MTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK
    产品特性
    Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 21/TNFRSF21 is produced with our HEK293 expression system. The target protein is expressed with sequence (Gln42-Leu350) of Human TNFRSF21 fused with a FC tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product TNFRSF21 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
    别名
    TNFRSF21 (TNFRSF21 产品)
    别名
    TNFRSF21 Protein, tnfrsf21 Protein, MGC146356 Protein, BM-018 Protein, CD358 Protein, DR6 Protein, AA959878 Protein, R74815 Protein, TR7 Protein, dr6 Protein, im:6795346 Protein, wu:fa55e01 Protein, wu:fb02e11 Protein, wu:fc29a09 Protein, wu:fi27h08 Protein, TNF receptor superfamily member 21 Protein, tumor necrosis factor receptor superfamily member 21 Protein, tumor necrosis factor receptor superfamily, member 21 Protein, TNFRSF21 Protein, tnfrsf21 Protein, Tnfrsf21 Protein
    Sub Type
    Fusionprotein
    背景
    Tumor Necrosis Factor Receptor Superfamily Member 21 (TNFRSF21) is a type I transmembrane receptor that includes four extracellular cysteine-rich motifs and a cytoplasmic death domain. DR6 is highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. DR6 may activate NF-kappa-B and JNK to promote apoptosis and T-cell differentiation. In addition, DR6 binds with N-APP, which is released by the deprivation of Trophic-factor. It triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). DR6 is also expressed on the tumor cell lines and can be induced by TNF-alpha.
    Alternative Names: Tumor Necrosis Factor Receptor Superfamily Member 21, Death Receptor 6, CD358, TNFRSF21, DR6, UNQ437/PRO868
    分子量
    61.7 kDa
    UniProt
    O75509
    途径
    Regulation of Lipid Metabolism by PPARalpha
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