POLD2 Protein (AA 1-469) (His tag)
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- 抗原 See all POLD2 蛋白
- POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-469
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This POLD2 protein is labelled with His tag.
- 原理
- Recombinant Human DNA Polymerase δ Subunit 2/POLD2 (C-6His)
- 序列
- MFSEQAAQRA HTLLSPPSAN NATFARVPVA TYTNSSQPFR LGERSFSRQY AHIYATRLIQ MRPFLENRAQ QHWGSGVGVK KLCELQPEEK CCVVGTLFKA MPLQPSILRE VSEEHNLLPQ PPRSKYIHPD DELVLEDELQ RIKLKGTIDV SKLVTGTVLA VFGSVRDDGK FLVEDYCFAD LAPQKPAPPL DTDRFVLLVS GLGLGGGGGE SLLGTQLLVD VVTGQLGDEG EQCSAAHVSR VILAGNLLSH STQSRDSINK AKYLTKKTQA ASVEAVKMLD EILLQLSASV PVDVMPGEFD PTNYTLPQQP LHPCMFPLAT AYSTLQLVTN PYQATIDGVR FLGTSGQNVS DIFRYSSMED HLEILEWTLR VRHISPTAPD TLGCYPFYKT DPFIFPECPH VYFCGNTPSF GSKIIRGPED QTVLLVTVPD FSATQTACLV NLRSLACQPI SFSGFGAEDD DLGGLGLGPL EHHHHHH
- 产品特性
- Recombinant Human DNA Polymerase Delta Subunit 2/POLD2 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Pro469) of Human POLD2 fused with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product POLD2 蛋白
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Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2) (AA 1-469) protein (GST tag)
POLD2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2) (AA 1-469) protein (Strep Tag)Crystallography grade POLD2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2) (AA 1-469) protein (Strep Tag)Crystallography grade POLD2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)POLD2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)POLD2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of PBS, 10 % Glycerol, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))
- 别名
- POLD2 (POLD2 产品)
- 别名
- 50kDa Protein, p50 Protein, po1D2 Protein, cdc1 Protein, si:dz150f13.3 Protein, zgc:55633 Protein, zgc:77043 Protein, DNA polymerase delta 2, accessory subunit Protein, polymerase (DNA directed), delta 2, regulatory subunit Protein, polymerase (DNA directed), delta 2, accessory subunit L homeolog Protein, POLD2 Protein, Pold2 Protein, pold2.L Protein, pold2 Protein
- Sub Type
- Fusionprotein
- 背景
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DNA Polymerase Delta Subunit 2 (POLD2) belongs to the DNA polymerase delta/II small subunit family. POLD2 can form a heterotetramer composed of subunits of 125 kDa, 50 kDa, 66 kDa and 12 kDa. POLD2 possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. POLD2 is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA).
Alternative Names: DNA Polymerase Delta Subunit 2, DNA Polymerase Delta Subunit p50, POLD2 - 分子量
- 52.3 kDa
- UniProt
- P49005
- 途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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