BLK Protein (AA 2-505) (His tag)
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- 抗原 See all BLK 蛋白
- BLK (B Lymphoid Tyrosine Kinase (BLK))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-505
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This BLK protein is labelled with His tag.
- 原理
- Recombinant Human Tyrosine-Protein Kinase Blk/BLK (C-6His)
- 序列
- GLVSSKKPDK EKPIKEKDKG QWSPLKVSAQ DKDAPPLPPL VVFNHLTPPP PDEHLDEDKH FVVALYDYTA MNDRDLQMLK GEKLQVLKGT GDWWLARSLV TGREGYVPSN FVARVESLEM ERWFFRSQGR KEAERQLLAP INKAGSFLIR ESETNKGAFS LSVKDVTTQG ELIKHYKIRC LDEGGYYISP RITFPSLQAL VQHYSKKGDG LCQRLTLPCV RPAPQNPWAQ DEWEIPRQSL RLVRKLGSGQ FGEVWMGYYK NNMKVAIKTL KEGTMSPEAF LGEANVMKAL QHERLVRLYA VVTKEPIYIV TEYMARGCLL DFLKTDEGSR LSLPRLIDMS AQIAEGMAYI ERMNSIHRDL RAANILVSEA LCCKIADFGL ARIIDSEYTA QEGAKFPIKW TAPEAIHFGV FTIKADVWSF GVLLMEVVTY GRVPYPGMSN PEVIRNLERG YRMPRPDTCP PELYRGVIAE CWRSRPEERP TFEFLQSVLE DFYTATERQY ELQPLEHHHH HH
- 产品特性
- Recombinant Human Tyrosine-Protein Kinase Blk/BLK is produced with our E. coli expression system. The target protein is expressed with sequence (Gly2-Pro505) of Human BLK fused with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product BLK 蛋白
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B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) (Active) protein (His-GST)
BLK 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) protein (GST tag)BLK 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
B Lymphoid Tyrosine Kinase (BLK) (AA 1-90) protein (GST tag)BLK 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) protein (His tag)BLK 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
B Lymphoid Tyrosine Kinase (BLK) (Active) protein (GST tag)BLK 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 88 % as determined by reducing SDS-PAGE. Active
B Lymphoid Tyrosine Kinase (BLK) (AA 2-505) protein (His tag)Crystallography grade BLK 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
B Lymphoid Tyrosine Kinase (BLK) (AA 2-499) protein (His tag)Crystallography grade BLK 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 500 mM NaCl, 1 mM DTT, pH 7.4.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- BLK (B Lymphoid Tyrosine Kinase (BLK))
- 别名
- Tyrosine-Protein Kinase Blk/BLK (BLK 产品)
- 别名
- bltk Protein, si:dkey-33i22.2 Protein, zgc:136231 Protein, MODY11 Protein, BLK proto-oncogene, Src family tyrosine kinase Protein, B lymphoid kinase Protein, blk Protein, BLK Protein, Blk Protein
- Sub Type
- Fusionprotein
- 背景
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Tyrosine-Protein Kinase Blk (BLK) contains one protein kinase domain, one SH2 domain and one SH3 domain. BLK is a non-receptor tyrosine kinase, which is involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulines and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. Defects in BLK are a cause of maturity-onset diabetes of the young type 11 (MODY11).
Alternative Names: Tyrosine-Protein Kinase Blk, B Lymphocyte Kinase, p55-Blk, BLK - 分子量
- 58.7 kDa
- UniProt
- P51451
- 途径
- Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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