IL-18 Protein (AA 37-193) (His tag)
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- 抗原 See all IL-18 (IL18) 蛋白
- IL-18 (IL18) (Interleukin 18 (IL18))
- 蛋白类型
- Recombinant
- 产品特性
- AA 37-193
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宿主
- 人
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资源
- 人细胞
- 标记
- This IL-18 protein is labelled with His tag.
- 原理
- Recombinant Human Interleukin-18/IL-18/IL-1F4 (C-6His)
- 序列
- YFGKLESKLS VIRNLNDQVL FIDQGNRPLF EDMTDSDCRD NAPRTIFIIS MYKDSQPRGM AVTISVKCEK ISTLSCENKI ISFKEMNPPD NIKDTKSDII FFQRSVPGHD NKMQFESSSY EGYFLACEKE RDLFKLILKK EDELGDRSIM FTVQNEDVDH HHHHH
- 产品特性
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Recombinant Human Interleukin-18/IL-18/IL-1F4 (C-6His)
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product IL18 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- IL-18 (IL18) (Interleukin 18 (IL18))
- 别名
- Interleukin-18/IL-18 (IL18 产品)
- 别名
- Igif Protein, Il-18 Protein, IL-18 Protein, IGIF Protein, ChIL-18 Protein, IL-1g Protein, IL1F4 Protein, IL18 Protein, interleukin 18 Protein, Il18 Protein, IL18 Protein
- 背景
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Recombinant Human Interleukin-18/IL-18 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Tyr37-Asp193) of Human IL-18 fused with a polyhistidine tag at the C-terminus.
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-γ production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells. - 分子量
- 23.3 kDa
- UniProt
- Q14116
- 途径
- Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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