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CD300a Protein (CD300A) (AA 18-178) (His tag,Fc Tag)

CD300A 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1691642
发货至: 中国
  • 抗原 See all CD300a (CD300A) 蛋白
    CD300a (CD300A)
    蛋白类型
    Recombinant
    产品特性
    AA 18-178
    宿主
    • 15
    • 7
    • 3
    • 1
    资源
    • 10
    • 6
    • 4
    • 3
    • 2
    • 1
    人细胞
    标记
    This CD300a protein is labelled with His tag,Fc Tag.
    原理
    Recombinant Human Leukocyte Mono Ig-Like Receptor 1/LMIR1/CD300a (C-Fc-6His)
    序列
    LSKCRTVAGP VGGSLSVQCP YEKEHRTLNK YWCRPPQIFL CDKIVETKGS AGKRNGRVSI RDSPANLSFT VTLENLTEED AGTYWCGVDT PWLRDFHDPV VEVEVSVFPA STSMTPASIT AAKTSTITTA FPPVSSTTLF AVGATHSASI QEETEEVVNS QVDDIEGRMD EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR EEMTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GKHHHHHH
    产品特性
    Recombinant Human CD300A is produced by our mammalian expression system. The target protein is expressed with sequence (Leu18-Gln178) of Human LMIR1CD300A fused with a FC-6xHis tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CD300A 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NACl,5 % Trehalose, pH 8.0.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    5 months
  • 抗原
    CD300a (CD300A)
    别名
    LMIR1CD300A (CD300A 产品)
    别名
    CD300L-B1 Protein, CD300A Protein, clm8 Protein, B230315M08Rik Protein, Clm8 Protein, LMIR1 Protein, MAIR-I Protein, MAIR-Ia Protein, MMAC8 Protein, Pigr4 Protein, mcpir1 Protein, CLM-8 Protein, CMRF-35-H9 Protein, CMRF-35H Protein, CMRF35-H Protein, CMRF35-H9 Protein, CMRF35H Protein, CMRF35H9 Protein, IGSF12 Protein, IRC1 Protein, IRC1/IRC2 Protein, IRC2 Protein, IRp60 Protein, CD300 molecule like family member g Protein, CD300a molecule Protein, CMRF35-like molecule 8 Protein, CD300A molecule Protein, Cd300a molecule Protein, CD300LG Protein, CD300A Protein, LOC483289 Protein, clm8 Protein, Cd300a Protein
    Sub Type
    Fusionprotein
    背景
    CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b, CD300e) and inhibitory members (CD300a, CD300f), as well as molecules presenting a negative charge within their transmembrane domain (CD300c, CD300d). It is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. CD300c is a functional immune receptor able to deliver activating signals upon ligation in RBL-2H3 mast cells.
    Alternative Names: CMRF35-like molecule 8, CD300 antigen-like family member A, CMRF-35-H9, CMRF35-H, IRC1/IRC2, Immunoglobulin superfamily member 12, Inhibitory receptor protein 60, NK inhibitory receptor
    分子量
    45.4 kDa
    UniProt
    Q9UGN4
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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