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ICAM1 Protein (AA 26-480) (Fc Tag)

ICAM1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1691618
发货至: 中国
  • 抗原 See all ICAM1 蛋白
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    蛋白类型
    Recombinant
    产品特性
    AA 26-480
    宿主
    • 17
    • 11
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 19
    • 12
    • 6
    • 3
    • 2
    • 2
    人细胞
    标记
    This ICAM1 protein is labelled with Fc Tag.
    原理
    Recombinant Human Intercellular Adhesion Molecule 1/ICAM-1/CD54 (C-Fc)
    序列
    NAQTSVSPSK VILPRGGSVL VTCSTSCDQP KLLGIETPLP KKELLLPGNN RKVYELSNVQ EDSQPMCYSN CPDGQSTAKT FLTVYWTPER VELAPLPSWQ PVGKNLTLRC QVEGGAPRAN LTVVLLRGEK ELKREPAVGE PAEVTTTVLV RRDHHGANFS CRTELDLRPQ GLELFENTSA PYQLQTFVLP ATPPQLVSPR VLEVDTQGTV VCSLDGLFPV SEAQVHLALG DQRLNPTVTY GNDSFSAKAS VSVTAEDEGT QRLTCAVILG NQSQETLQTV TIYSFPAPNV ILTKPEVSEG TEVTVKCEAH PRAKVTLNGV PAQPLGPRAQ LLLKATPEDN GRSFSCSATL EVAGQLIHKN QTRELRVLYG PRLDERDCPG NWTWPENSQQ TPMCQAWGNP LPELKCLKDG TFPLPIGESV TVTRDLEGTY LCRARSTQGE VTRKVTVNVL SPRYEVDDIE GRMDEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSREEMTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGK
    产品特性
    Recombinant Human Intercellular Adhesion Molecule 1/ICAM-1 is produced by our mammalian expression system. The target protein is expressed with sequence (Asn26 ­ Glu480) ofHuman CD54 fused with a FC tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product ICAM1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    5 months
  • 抗原
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    别名
    CD54 (ICAM1 产品)
    别名
    BB2 Protein, CD54 Protein, P3.58 Protein, Icam-1 Protein, Ly-47 Protein, MALA-2 Protein, ICAM Protein, ICAM-1 Protein, ICAM1 Protein, intercellular adhesion molecule 1 Protein, intercellular adhesion molecule-1 Protein, ICAM1 Protein, Icam1 Protein, ICAM-1 Protein
    Sub Type
    Fusionprotein
    物质类
    Viral Protein
    背景
    Inter-Cellular Adhesion Molecule 1 (ICAM1) is a type of intercellular adhesion molecule continuously present in low concentrations in the membranes of leukocytes and endothelial cells. As an endothelial and leukocyte-associated transmembrane protein, ICAM1 is well known for its importance in stabilizing cell-cell interactions and facilitating leukocyte endothelial transmigration. The presence of heavy glycosylation and other structural characteristics lend ICAM1 binding sites for a number of immune-associated ligands. Notably, ICAM-1 binds to macrophage adhesion ligand-1 (Mac-1, ITGB2 / ITGAM), leukocyte function associated antigen-1 (LFA-1/integrin), and fibrinogen.ICAM-1 expressed by respiratory epithelial cells is also the binding site for rhinovirus, the causative agent of most common colds.
    Alternative Names: Intercellular Adhesion Molecule 1, ICAM-1, Major Group Rhinovirus Receptor, CD54, ICAM1
    分子量
    76.8 kDa
    UniProt
    P05362
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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