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SGSH Protein (AA 21-502) (His tag)

SGSH 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1691380
发货至: 中国
  • 抗原 See all SGSH 蛋白
    SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))
    蛋白类型
    Recombinant
    产品特性
    AA 21-502
    宿主
    • 4
    • 2
    资源
    • 3
    • 1
    • 1
    • 1
    人细胞
    标记
    This SGSH protein is labelled with His tag.
    原理
    Recombinant Human N-Sulphoglucosamine Sulphohydrolase/SGSH (C-6His)
    序列
    RPRNALLLLA DDGGFESGAY NNSAIATPHL DALARRSLLF RNAFTSVSSC SPSRASLLTG LPQHQNGMYG LHQDVHHFNS FDKVRSLPLL LSQAGVRTGI IGKKHVGPET VYPFDFAYTE ENGSVLQVGR NITRIKLLVR KFLQTQDDRP FFLYVAFHDP HRCGHSQPQY GTFCEKFGNG ESGMGRIPDW TPQAYDPLDV LVPYFVPNTP AARADLAAQY TTVGRMDQGV GLVLQELRDA GVLNDTLVIF TSDNGIPFPS GRTNLYWPGT AEPLLVSSPE HPKRWGQVSE AYVSLLDLTP TILDWFSIPY PSYAIFGSKT IHLTGRSLLP ALEAEPLWAT VFGSQSHHEV TMSYPMRSVQ HRHFRLVHNL NFKMPFPIDQ DFYVSPTFQD LLNRTTAGQP TGWYKDLRHY YYRARWELYD RSRDPHETQN LATDPRFAQL LEMLRDQLAK WQWETHDPWV CAPDGVLEEK LSPQCQPLHN ELVDHHHHHH
    产品特性
    Recombinant Human N-Sulphoglucosamine Sulphohydrolase/SGSH is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Arg21-Leu502) of Human SGSH fused with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product SGSH 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM GaCl2,10 % Glycerol, pH 7.5.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    -80 °C
    储存方法
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))
    Abstract
    SGSH 产品
    别名
    HSS Protein, MPS3A Protein, SFMD Protein, 4632406A19Rik Protein, N-sulfoglucosamine sulfohydrolase Protein, N-sulfoglucosamine sulfohydrolase (sulfamidase) Protein, SGSH Protein, Sgsh Protein
    Sub Type
    Fusionprotein
    背景
    N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.
    Alternative Names: N-Sulphoglucosamine Sulphohydrolase, Sulfoglucosamine Sulfamidase, Sulphamidase, SGSH, HSS
    分子量
    55.72 kDa
    UniProt
    P51688
    途径
    Glycosaminoglycan Metabolic Process
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