MAN1B1 Protein (AA 106-699) (His tag)
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- 抗原 See all MAN1B1 蛋白
- MAN1B1 (Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 106-699
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宿主
- 人
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资源
- 人细胞
- 标记
- This MAN1B1 protein is labelled with His tag.
- 原理
- Recombinant Human ER α-1,2-Mannosidase/MAN1B1 (C-6His)
- 序列
- DHWKALAFRL EEEQKMRPEI AGLKPANPPV LPAPQKADTD PENLPEISSQ KTQRHIQRGP PHLQIRPPSQ DLKDGTQEEA TKRQEAPVDP RPEGDPQRTV ISWRGAVIEP EQGTELPSRR AEVPTKPPLP PARTQGTPVH LNYRQKGVID VFLHAWKGYR KFAWGHDELK PVSRSFSEWF GLGLTLIDAL DTMWILGLRK EFEEARKWVS KKLHFEKDVD VNLFESTIRI LGGLLSAYHL SGDSLFLRKA EDFGNRLMPA FRTPSKIPYS DVNIGTGVAH PPRWTSDSTV AEVTSIQLEF RELSRLTGDK KFQEAVEKVT QHIHGLSGKK DGLVPMFINT HSGLFTHLGV FTLGARADSY YEYLLKQWIQ GGKQETQLLE DYVEAIEGVR THLLRHSEPS KLTFVGELAH GRFSAKMDHL VCFLPGTLAL GVYHGLPASH MELAQELMET CYQMNRQMET GLSPEIVHFN LYPQPGRRDV EVKPADRHNL LRPETVESLF YLYRVTGDRK YQDWGWEILQ SFSRFTRVPS GGYSSINNVQ DPQKPEPRDK MESFFLGETL KYLFLLFSDD PNLLSLDAYV FNTEAHPLPI WTPAVDHHHH HH
- 产品特性
- Recombinant Human Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-alpha-Mannosidase/MAN1B1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Asp106-Ala699) of Human MAN1B1 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product MAN1B1 蛋白
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Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) (AA 112-211) protein (GST tag)
MAN1B1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) (AA 1-699) protein (Strep Tag)Crystallography grade MAN1B1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) (AA 106-699) protein (His tag)Crystallography grade MAN1B1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) (AA 72-658) protein (His tag)Crystallography grade MAN1B1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) (AA 1-658) protein (Strep Tag)Crystallography grade MAN1B1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 50 mM TrisHCL,10 mM reduced Glutathione, pH 8.0.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- MAN1B1 (Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1))
- 别名
- MAN1B1 (MAN1B1 产品)
- 别名
- erman1 Protein, mana-er Protein, MAN1B1 Protein, ERMAN1 Protein, MANA-ER Protein, MRT15 Protein, E430019H13Rik Protein, ERMan1 Protein, Gm108 Protein, RGD1563595 Protein, mannosidase alpha class 1B member 1 Protein, mannosidase, alpha, class 1B, member 1 L homeolog Protein, endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase Protein, mannosidase, alpha, class 1B, member 1 Protein, MAN1B1 Protein, man1b1.L Protein, LOC480667 Protein, man1b1 Protein, Man1b1 Protein
- Sub Type
- Fusionprotein
- 背景
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Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-alpha-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. MAB1B1 can be inhibited by both 1-deoxymannojirimycin (dMNJ) and kifunensine. Defects in MAN1B1 are the cause of mental retardation autosomal recessive type 15 (MRT15). Mental retardation is characterized by significantly below average general intellectual functioning, it is also associated with impairments in adaptative behavior and manifested during the developmental period.
Alternative Names: Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-Alpha-Mannosidase, ER Alpha-1,2-Mannosidase, ER Mannosidase 1, ERMan1, Man9GlcNAc2-Specific-Processing Alpha-Mannosidase, Mannosidase Alpha Class 1B Member 1, MAN1B1 - 分子量
- 68.7 kDa
- UniProt
- Q9UKM7
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