Periostin Protein (POSTN) (AA 24-783, Isoform 5) (DYKDDDDK Tag)
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- 抗原 See all Periostin (POSTN) 蛋白
- Periostin (POSTN)
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- Isoform 5, AA 24-783
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宿主
- 小鼠
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资源
- CHO Cells
- 标记
- This Periostin protein is labelled with DYKDDDDK Tag.
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 小鼠
- 产品特性
- Mouse periostin (aa 24-783) (isoform 5) is fused at the C-terminus to a FLAG®-tag.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product POSTN 蛋白
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Periostin (POSTN) (AA 22-836) protein (His tag)
POSTN 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Periostin (POSTN) (AA 24-811) protein (His tag)POSTN 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Periostin (POSTN) (Active) protein (His tag)POSTN 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE Active
Periostin (POSTN) (Active) protein (His tag)POSTN 宿主: 人 宿主: HEK-293 Cells Recombinant > 97 % as determined by reducing SDS-PAGE. Active
Periostin (POSTN) (AA 22-836) protein (His tag)Crystallography grade POSTN 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Periostin (POSTN) (AA 24-838) protein (His tag)Crystallography grade POSTN 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Rescues sphere formation from periostin KO primary tumor cells at 50ng/ml.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with 100 μL sterile water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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- 抗原
- Periostin (POSTN)
- 别名
- Periostin (POSTN 产品)
- 别名
- fa99h07 Protein, pn Protein, postn Protein, wu:fa99h07 Protein, wu:fc70f09 Protein, zgc:153873 Protein, LOC100008945 Protein, osf-2 Protein, pdlpostn Protein, periostin Protein, OSF-2 Protein, OSF2 Protein, PDLPOSTN Protein, PN Protein, RP11-412K4.1 Protein, A630052E07Rik Protein, AI747096 Protein, Osf2 Protein, PLF Protein, peri Protein, Plf Protein, periostin Protein, periostin, osteoblast specific factor b Protein, periostin, osteoblast specific factor Protein, POSTN Protein, postnb Protein, postn Protein, Postn Protein
- 背景
- Periostin is a 90- kDa matricellular protein that consists of a typical signal sequence, followed by a cysteine-rich region, an EMI domain (protein-protein interactions), four tandem fasciclin-like domains that are responsible for integrin binding, and a C-terminal region. Periostin was originally isolated as an osteoblast-specific factor that functions as a cell adhesion molecule for pre-osteoblasts and in osteoblast recruitment, attachment and spreading. Periostin is also involved in many fundamental biological processes such as cell proliferation, cell invasion and angiogenesis. Periostin expression is increased by both transforming growth factor beta1 (TGF-beta1) and bone morphogenetic protein 2 (BMP-2). Changes in periostin expression are commonly detected in various cancers and pre-cancerous conditions, and periostin may be involved in regulating cancer cell activities that contribute to tumorigenesis, cancer progression and metastasis. Periostin has shown to be involved in many aspects of allergic inflammation, such as eosinophil recruitment, airway remodeling, development of a Th2 phenotype and increased expression of inflammatory mediators. It is evaluated as a biomarker for bronchial asthma and airway inflammation.
- 分子量
- ~85kDa
- UniProt
- Q62009
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