IL1R1 Protein (AA 21-336) (Fc Tag)
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- 抗原 See all IL1R1 蛋白
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 21-336
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL1R1 protein is labelled with Fc Tag.
- 应用范围
- SDS-PAGE (SDS)
- 特异性
- Binds to human IL-1beta.
- 交叉反应
- 人
- 产品特性
- Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product IL1R1 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Blocks IL-1beta activity.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with 50 μL sterile water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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- 抗原
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
- Abstract
- IL1R1 产品
- 别名
- CD121A Protein, D2S1473 Protein, IL-1R-alpha Protein, IL1R Protein, IL1RA Protein, P80 Protein, CD121a Protein, CD121b Protein, IL-iR Protein, Il1r-1 Protein, DER4 Protein, Fit-1 Protein, Ly84 Protein, ST2L Protein, St2 Protein, St2-rs1 Protein, T1 Protein, T1/ST2 Protein, interleukin 1 receptor type 1 Protein, interleukin 1 receptor, type I Protein, interleukin 1 receptor-like 1 Protein, IL1R1 Protein, Il1r1 Protein, Il1rl1 Protein
- 背景
- IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2.
- 分子量
- ~80kDa (SDS-PAGE)
- UniProt
- P14778
- 途径
- NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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