IL1F9 Protein (AA 13-164) (DYKDDDDK Tag)
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- 抗原 See all IL1F9 蛋白
- IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 13-164
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宿主
- 小鼠
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资源
- 大肠杆菌(E. Coli)
- 标记
- This IL1F9 protein is labelled with DYKDDDDK Tag.
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 小鼠
- 产品特性
- Mouse IL-36gamma (aa Gly13-Ser164) is fused at the C-terminus to a FLAG®-tag.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product IL1F9 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Induces secretion of IL-6 in BMDCs.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with 100 μL sterile water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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- 抗原
- IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
- 别名
- IL-36 gamma (IL1F9 产品)
- 背景
- IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
- 分子量
- ~17kDa
- UniProt
- Q8R460
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