IDO1 Protein (AA 1-407) (His tag)
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- 抗原 See all IDO1 蛋白
- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 1-407
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This IDO1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 小鼠
- 产品特性
- Mouse IDO (aa 1-407) is fused at the C-terminus to a His-tag.
- 纯度
- >90 % (SDS-PAGE)
- 过滤
- 0.2 μm filtered
- 内毒素水平
- <1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product IDO1 蛋白
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Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) protein (His tag)
IDO1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) protein (GST tag)IDO1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Indoleamine 2,3-Dioxygenase 1 (IDO1) protein (His tag)IDO1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 304-403) protein (GST tag)IDO1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Indoleamine 2,3-Dioxygenase 1 (IDO1) (Active) proteinIDO1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % as determined by reducing SDS-PAGE. Active
Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) protein (Strep Tag)Crystallography grade IDO1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-407) protein (Strep Tag)Crystallography grade IDO1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Indoleamine 2,3-Dioxygenase 1 (IDO1) (Active) protein (Myc-DYKDDDDK Tag)IDO1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Specific Activity: >100'000U/mg protein with L-tryptophan as substrate and after addition of 7μM hemin for protein induction. One unit is defined as the amount of enzyme that produces 1nmol of kynurenine per hour.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- 0.2μm-filtered solution in 50 mM TRIS-Cl, pH 7.4, containing 1 mM EDTA.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - 有效期
- 3 months
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- 抗原
- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
- 别名
- IDO (IDO1 产品)
- 别名
- INDO Protein, ido Protein, indo Protein, IDO Protein, cd107b Protein, IDO1 Protein, IDO-1 Protein, Ido Protein, Indo Protein, indoleamine 2,3-dioxygenase 1 Protein, indoleamine 2,3-dioxygenase 1 L homeolog Protein, indoleamine 2,3-dioxygenase 1-like Protein, IDO1 Protein, ido1.L Protein, ido1 Protein, Ido1 Protein, LOC100050681 Protein
- 背景
- IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.
- 分子量
- ~40kDa (SDS-PAGE)
- UniProt
- P28776
- 途径
- Activated T Cell Proliferation
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