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TK1 Protein (His tag)

TK1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN1098640
发货至: 中国
  • 抗原 See all TK1 蛋白
    TK1 (Thymidine Kinase 1, Soluble (TK1))
    蛋白类型
    Recombinant
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    资源
    • 59
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    大肠杆菌(E. Coli)
    标记
    This TK1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯化方法
    purified by using conventional chromatography.
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product TK1 蛋白
  • 说明

    Synonyms: Thymidine kinase, cytosolic, TK2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1 M NaCl, 1 MM DTT
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    TK1 (Thymidine Kinase 1, Soluble (TK1))
    别名
    TK1 (TK1 产品)
    别名
    fi19b06 Protein, zgc:55362 Protein, wu:fi19b06 Protein, TK1 Protein, tk2 Protein, D530002A18Rik Protein, Tk-1 Protein, Tk1a Protein, Tk1b Protein, TK2 Protein, Tk Protein, TK Protein, thymidine kinase 1, soluble Protein, thymidine kinase 1 Protein, thymidine kinase, cytosolic Protein, Thymidine kinase, cytosolic Protein, temporal expression: early Protein, thymidine kinase Protein, Tk thymidine kinase Protein, tk1 Protein, TK1 Protein, EDI_049980 Protein, kith Protein, J2R Protein, HVT031 Protein, Tk1 Protein, tk Protein
    背景
    TK1, also known as thymidine kinase, is an enzyme, a phosphotransferase (a kinase): 2'-deoxythymidine kinase, ATP-thymidine 5'-phosphotransferase. It is present in two forms in mammalian cells, TK1 and TK2. Thymidine kinases have a key function in the synthesis of DNA and thereby in cell division, as they are part of the unique reaction chain to introduce deoxythymidine into the DNA. Deoxythymidine is present in the body fluids as a result of degradation of DNA from food and from dead cells. Thymidine kinase is required for the action of many antiviral drugs. It is used to select hybridoma cell lines in production of monoclonal antibodies. In clinical chemistry it is used as a proliferation marker in the diagnosis, control of treatment and follow-up of malignant disease, mainly of hematological malignancies. Recombinant human TK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
    分子量
    28.0 kDa (258aa) confirmed by MALDI-TOF
    NCBI登录号
    NP_003249
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