D-tyrosyl-tRNA Deacylase 1 Homolog (S. Cerevisiae) (DTD1) protein (His tag)

ABIN1098471 产品详细信息, 供应商: Log in to see
蛋白名称
  • 0610006H08Rik
  • Hars2
  • C20orf88
  • DUEB
  • HARS2
  • bA379J5.3
  • bA555E18.1
  • pqn-68
  • hars2
  • zgc:92657
  • D-tyrosyl-tRNA deacylase 1
  • Dtd1
  • DTD1
  • dtd1
宿主

7
1
1
资源
大肠杆菌(E. Coli)
4
2
1
1
1
蛋白类型
Recombinant
标记
His tag
应用范围
SDS-PAGE (SDS)
选项
Supplier
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Supplier Product No.
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纯化方法 purified by chromatography
纯度 > 85 % by SDS - PAGE
蛋白名称
背景 DTD1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). It could be a defense mechanism against a harmful effect of D-tyrosine. DTD1 may be a risk factor for aspirin-intolerant asthma (AIA) by catalyzing the hydrolysis of D-tryptophan and interacting with the tyrosyl-tRNA synthetase (tyrRS) enzyme, which promotes a pro-inflammatory phenotype. This protein is localize to the DUE(DNA unwinding element )s of active replication origins. Recombinant human DTD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
分子量 25.9kDa (232aa) confirmed by MALDI-TOF
NCBI登录号 NP_543010
说明

Synonyms: D-tyrosyl-tRNA deacylase 1, bA379J5.3, bA555E18.1, C20orf88, DUEB, HARS2, pqn-68

限制 仅限研究用
状态 Liquid
浓度 0.5 mg/ml (determined by Bradford assay)
缓冲液 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol, 1 MM DTT
储存条件 4 °C
储存方法 Avoid repeated freezing and thawing cycles.
厂商提供的图像
 image for D-tyrosyl-tRNA Deacylase 1 Homolog (S. Cerevisiae) (DTD1) protein (His tag) (ABIN1098471) D-tyrosyl-tRNA Deacylase 1 Homolog (S. Cerevisiae) (DTD1) protein (His tag)
背景 Pasaje, Bae, Park, Jang, Uh, Kim, Koh, Kim, Park, Lee, Kim, Park, Shin: "Association analysis of DTD1 gene variations with aspirin-intolerance in asthmatics." in: International journal of molecular medicine, Vol. 28, Issue 1, pp. 129-37, 2011 (PubMed).

Chowdhury, Liu, Kemp, Chen, Katrangi, Myers, Ghosh, Yao, Gao, Bubulya, Leffak: "The DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation." in: Molecular and cellular biology, Vol. 30, Issue 6, pp. 1495-507, 2010 (PubMed).

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