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Tissue factor Protein (His tag)

F3 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN1098373
发货至: 中国
  • 抗原 See all Tissue factor (F3) 蛋白
    Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
    蛋白类型
    Recombinant
    宿主
    • 16
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    • 4
    • 3
    • 2
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    • 1
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    资源
    • 14
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    大肠杆菌(E. Coli)
    标记
    This Tissue factor protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯化方法
    purified by chromatography
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product F3 蛋白
  • 说明

    Synonyms: Tissue factor, CD142, TF, TFA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol,1 MM DTT
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
    别名
    F3 (F3 产品)
    别名
    CD142 Protein, TF Protein, TFA Protein, PRO1557 Protein, PRO2086 Protein, TFQTL1 Protein, f3 Protein, AA409063 Protein, Cf-3 Protein, Cf3 Protein, tf Protein, zgc:112151 Protein, coagulation factor III, tissue factor Protein, transferrin Protein, coagulation factor IIIa Protein, coagulation factor III Protein, tissue factor Protein, coagulation factor IIIb Protein, coagulation factor III (thromboplastin, tissue factor) S homeolog Protein, F3 Protein, TF Protein, f3a Protein, tf Protein, f3b Protein, f3.S Protein
    背景
    Tissue factor, also known as F3 or CD142, is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Recombinant human F3 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    25.9 kDa (228aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
    NCBI登录号
    NP_001984
    途径
    Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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