Recombinant Human Serpin Peptidase Inhibitor, Clade A, Member 6 /Serpin A6 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Met23-Val405) of Human Serpin A6 fused with a polyhistidine tag at the C-terminus.
纯度
> 95 % as determined by reducing SDS-PAGE.
过滤
0.2 μm filtered
内毒素水平
Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
缓冲液
Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
注意事项
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
储存条件
4 °C/-20 °C/-80 °C
储存方法
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
有效期
3 months
抗原
SERPINA6
(serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6))
ep45-A Protein, SERPINA6 Protein, AI265318 Protein, AV104445 Protein, Cbg Protein, CBG Protein, serpin family A member 6 Protein, serpin family A member 6 L homeolog Protein, corticosteroid-binding globulin Protein, serine (or cysteine) peptidase inhibitor, clade A, member 6 Protein, SERPINA6 Protein, serpina6.L Protein, LOC490838 Protein, Serpina6 Protein
Sub Type
Fusionprotein
背景
Serpin Peptidase Inhibitor, Clade A, Member 6 (SerpinA6) belongs to the Serine Protease Inhibitors superfamily. SerpinA6 is synthesized in liver and has also been identified in a number of glycocorticoid responsive cells. SerpinA6 has an alpha-globulin protein with corticosteroid-binding properties. It is the major transport protein for glucocorticoids and progestins in the blood of most vertebrates. Defects in SERPINA6 are a cause of corticosteroid-binding globulin deficiency which is an extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue. Alternative Names: Corticosteroid-Binding Globulin, CBG, Serpin A6, Transcortin, SERPINA6, CBG