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GPA33 Protein (AA 22-235) (His tag)

GPA33 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1096759
发货至: 中国
  • 抗原 See all GPA33 蛋白
    GPA33 (Glycoprotein A33 (Transmembrane) (GPA33))
    蛋白类型
    Recombinant
    产品特性
    AA 22-235
    宿主
    • 11
    • 3
    • 1
    • 1
    资源
    • 8
    • 4
    • 2
    • 1
    • 1
    人细胞
    标记
    This GPA33 protein is labelled with His tag.
    原理
    Recombinant Human Glycoprotein A33/GPA33/GPA33 (C-6His)
    序列
    ISVETPQDVL RASQGKSVTL PCTYHTSTSS REGLIQWDKL LLTHTERVVI WPFSNKNYIH GELYKNRVSI SNNAEQSDAS ITIDQLTMAD NGTYECSVSL MSDLEGNTKS RVRLLVLVPP SKPECGIEGE TIIGNNIQLT CQSKEGSPTP QYSWKRYNIL NQEQPLAQPA SGQPVSLKNI STDTSGYYIC TSSNEEGTQF CNITVAVRSP SMNVVDHHHH HH
    产品特性

    Recombinant Human Glycoprotein A33/GPA33/GPA33 (C-6His)

    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product GPA33 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    GPA33 (Glycoprotein A33 (Transmembrane) (GPA33))
    别名
    Glycoprotein A33/GPA33 (GPA33 产品)
    别名
    A33 Protein, 2010310L10Rik Protein, 2210401D16Rik Protein, BB116197 Protein, glycoprotein A33 Protein, glycoprotein A33 (transmembrane) Protein, GPA33 Protein, Gpa33 Protein
    背景
    Recombinant Human Glycoprotein A33/GPA33 produced by transfected human cells is a secreted protein with sequence (Ile22-Val235) of Human GPA33 fused with a polyhistidine tag at the C-terminus.
    Human Glycoprotein A33 (GPA33) is a single-pass type I membrane protein, belongs to the CTX family of cell adhesion molecular within the immunoglobulin family, can be expressed in normal gastrointestinal epithelium and in 95 % of colon cancers. GPA33 consists of one Ig-like C2-type domain and one Ig-like V-type domain. The predicted mature protein includes a single transmembrane domain, a extracellular region and a intracellular tail. Intracellular traffic and recycling to the cell surface appear to play an important role in GPA33 function and to have an influence on its surface density superseding translation regulation. GPA33 has become a promising target of immunologic therapy strategies. GPA33 may also play a important role in cell-cell recognition and signaling.
    分子量
    24.66 kDa
    UniProt
    Q99795
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