PROCR Protein (AA 18-210) (His tag)
-
- 抗原 See all PROCR 蛋白
- PROCR (Protein C Receptor, Endothelial (PROCR))
- 蛋白类型
- Recombinant
- 产品特性
- AA 18-210
-
宿主
- 人
-
资源
- 人细胞
- 标记
- This PROCR protein is labelled with His tag.
- 原理
- Recombinant Human Endothelial Protein C Receptor/EPCR/PROCR/CD201 (C-6His)
- 序列
- SQDASDGLQR LHMLQISYFR DPYHVWYQGN ASLGGHLTHV LEGPDTNTTI IQLQPLQEPE SWARTQSGLQ SYLLQFHGLV RLVHQERTLA FPLTIRCFLG CELPPEGSRA HVFFEVAVNG SSFVSFRPER ALWQADTQVT SGVVTFTLQQ LNAYNRTRYE LREFLEDTCV QYVQKHISAE NTKGSQTSRS YTSVDHHHHH H
- 产品特性
- Recombinant Human Endothelial Protein C Receptor/EPCR is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Ser18-Ser210) of Human EPCR fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PROCR 蛋白
-
Protein C Receptor, Endothelial (PROCR) (AA 1-238) protein (GST tag)
PROCR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Protein C Receptor, Endothelial (PROCR) protein (His tag)PROCR 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Protein C Receptor, Endothelial (PROCR) protein (His tag)PROCR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE
Protein C Receptor, Endothelial (PROCR) protein (Fc Tag)PROCR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
Protein C Receptor, Endothelial (PROCR) (AA 18-210) protein (His tag)Crystallography grade PROCR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein C Receptor, Endothelial (PROCR) (AA 18-214) protein (His tag)Crystallography grade PROCR 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein C Receptor, Endothelial (PROCR) (AA 18-238) protein (rho-1D4 tag)Crystallography grade PROCR 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein C Receptor, Endothelial (PROCR) (AA 18-242) protein (rho-1D4 tag)Crystallography grade PROCR 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
-
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
-
- 抗原
- PROCR (Protein C Receptor, Endothelial (PROCR))
- 别名
- epcr (PROCR 产品)
- 别名
- PROCR Protein, CCCA Protein, CCD41 Protein, EPCR Protein, AI325044 Protein, Ccca Protein, Ccd41 Protein, Epcr Protein, protein C receptor Protein, protein C receptor, endothelial Protein, PROCR Protein, Procr Protein
- Sub Type
- Fusionprotein
- 背景
-
Endothelial Protein C Receptor (EPCR) is a Vitamin K-dependent Serine Protease that plays a major role in blood coagulation. Binding of Protein C to EPCR leads to the proteolytic activation of PAR1 (Protease-Activated Receptor 1) on endothelial cells and subsequent up-regulation of Protein C-induced genes. EPCR is a type I transmembrane glycoprotein in the CD1/MHC family. It is expressed most strongly in the endothelial cells of arteries and veins in heart and lung. Membrane bound EPCR is released by metalloproteolytic cleavage to generate the soluble receptor. The extracellular domain of human and mouse EPCR shares approximately 61% amino acid sequence homology. EPCR plays an important role in augmenting Protein C activation by the Thrombin-Thrombomodulin complex and in regulating blood coagulation and inflammation. EPCR is found primarily on endothelial cells. Deletion of EPCR function results in embryonic death, at least in part due to placental thrombosis.
Alternative Names: Endothelial Protein C Receptor, Activated Protein C Receptor, APC Receptor, Endothelial Cell Protein C Receptor, CD201, PROCR, EPCR - 分子量
- 23.06 kDa
- UniProt
- Q9UNN8
-
