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TNF alpha Protein (AA 78-234) (His tag)

TNF alpha 宿主: Cow 宿主: 大肠杆菌(E. Coli) Recombinant 95 % SDS, ELISA
产品编号 ABIN1047832
发货至: 中国
  • 抗原 See all TNF alpha 蛋白
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    蛋白类型
    Recombinant
    产品特性
    AA 78-234
    宿主
    • 41
    • 23
    • 11
    • 6
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    • 4
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    Cow
    资源
    • 57
    • 28
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This TNF alpha protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS), ELISA
    序列
    LRSSSQASSN KPVAHVVADI NSPGQLRWWD SYANALMANG VKLEDNQLVV PADGLYLIYS QVLFRGQGCP STPLFLTHTI SRIAVSYQTK VNILSAIKSP CHRETPEWAE AKPWYEPIYQ GGVFQLEKGD RLSAEINLPD YLDYAESGQV YFGIIAL
    产品特性
    Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
    纯度
    95 %
    Top Product
    Discover our top product TNF alpha 蛋白
  • 说明

    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    20mM Tris-Hcl, 0.5M NaCl, 10% glycerin, PH 8.0, 200 mM Imidazole
    储存条件
    -20 °C
  • Dietz, Neibergs, Womack, Kehrli: "Rapid communication: single strand conformational polymorphism (SSCP) of bovine tumor necrosis factor alpha." in: Journal of animal science, Vol. 75, Issue 9, pp. 2567, (1997) (PubMed).

    Mertens, Muriuki, Gaidulis: "Cloning of two members of the TNF-superfamily in cattle: CD40 ligand and tumor necrosis factor alpha." in: Immunogenetics, Vol. 42, Issue 5, pp. 430-1, (1995) (PubMed).

  • 抗原
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    别名
    Tumor necrosis factor (TNF alpha 产品)
    别名
    DIF Protein, TNF-alpha Protein, TNFA Protein, TNFSF2 Protein, RATTNF Protein, Tnfa Protein, tnf Protein, TNF-a Protein, TNFalpha Protein, Tnfsf1a Protein, TNFa Protein, cTNF Protein, Tnf-alpha Protein, tnfa-like Protein, TNF-ALPHA Protein, dif Protein, tnfa Protein, xtnf Protein, tnfsf2 Protein, tnf-alpha Protein, Cachectin Protein, tumor necrosis factor Protein, tumor necrosis factor b (TNF superfamily, member 2) Protein, tumor necrosis factor alpha Protein, tumor necrosis factor a (TNF superfamily, member 2) Protein, TNF Protein, Tnf Protein, tnf Protein, tnfb Protein, tnf-alpha Protein, LOC103694380 Protein, tnfa Protein
    背景
    Synonyms: Cachectin,TNF-alpha,Tumor necrosis factor ligand superfamily member 2,TNF-a
    分子量
    21.5 kD
    UniProt
    Q06599
    途径
    NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
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