HNRNPD/AUF1 Protein (AA 18-355, partial) (GST tag)
(3 references)-
- 抗原 See all HNRNPD/AUF1 (HNRNPD) 蛋白
- HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
- 蛋白类型
- Recombinant
- 产品特性
- AA 18-355, partial
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This HNRNPD/AUF1 protein is labelled with GST tag.
- 应用范围
- SDS-PAGE (SDS), ELISA
- 序列
- AVGGSAGEQE GAMVAATQGA AAAAGSGAGT GGGTASGGTE GGSAESEGAK IDASKNEEDE GHSNSSPRHS EAATAQREEW KMFIGGLSWD TTKKDLKDYF SKFGEVVDCT LKLDPITGRS RGFGFVLFKE SESVDKVMDQ KEHKLNGKVI DPKRAKAMKT KEPVKKIFVG GLSPDTPEEK IREYFGGFGE VESIELPMDN KTNKRRGFCF ITFKEEEPVK KIMEKKYHNV GLSKCEIKVA MSKEQYQQQQ QWGSRGGFAG RARGRGGDQQ SGYGKVSRRG GHQNSYKPY
- 产品特性
- Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Ref.13 Ref.30
- 纯度
- 90 %
- Top Product
- Discover our top product HNRNPD 蛋白
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Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD) (AA 1-355) protein (GST tag)
HNRNPD 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD) (AA 2-355) protein (His tag)Crystallography grade HNRNPD 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD) (AA 2-355) protein (His tag)Crystallography grade HNRNPD 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)HNRNPD 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)HNRNPD 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)HNRNPD 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)HNRNPD 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 说明
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Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS buffer, 20mM GSH
- 储存条件
- -20 °C
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: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).
: "The human HNRPD locus maps to 4q21 and encodes a highly conserved protein." in: Genomics, Vol. 49, Issue 3, pp. 378-84, (1998) (PubMed).
: "The UUAG-specific RNA binding protein, heterogeneous nuclear ribonucleoprotein D0. Common modular structure and binding properties of the 2xRBD-Gly family." in: The Journal of biological chemistry, Vol. 270, Issue 38, pp. 22167-75, (1995) (PubMed).
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: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).
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- 抗原
- HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
- 别名
- Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD 产品)
- 别名
- AUF1 Protein, AUF1A Protein, HNRPD Protein, P37 Protein, hnRNPD0 Protein, Auf1 Protein, Hnrnpd Protein, HNRNPD Protein, p37 Protein, auf1a Protein, hnrpd Protein, hnrnpd0 Protein, C230004L04 Protein, Hnrpd Protein, wu:fa28b06 Protein, zgc:162951 Protein, heterogeneous nuclear ribonucleoprotein D Protein, heterogeneous nuclear ribonucleoprotein D L homeolog Protein, HNRNPD Protein, Hnrnpd Protein, hnrnpd Protein, hnrnpd.L Protein
- 背景
- Synonyms: AU-rich element RNA-binding protein 1
- 分子量
- 58.6 kD
- UniProt
- Q14103
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