抗原 See all ADAR 蛋白: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))
蛋白类型: Recombinant
产品特性: AA 1-176, partial
宿主 4 1: 人
资源 1 1 1 1 1: 大肠杆菌（E. Coli）
标记: This ADAR protein is labelled with His-SUMO Tag.
应用范围: ELISA
序列: MNPRQGYSLS GYYTHPFQGY EHRQLRYQQP GPGSSPSSFL LKQIEFLKGQ LPEAPVIGKQ TPSLPPSLPG LRPRFPVLLA SSTRGRQVDI RGVPRGVHLG SQGLQRGFQH PSPRGRSLPQ RGVDCLSSHF QELSIYQDQE QRILKFLEEL GEGKATTAHD LSGKLGTPKK EINRVL
产品特性: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
纯度: 90 %
Top Product: Discover our top product ADAR 蛋白

Adenosine Deaminase, RNA-Specific (ADAR) (AA 2-110) protein (GST tag)

ADAR 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

Adenosine Deaminase, RNA-Specific (ADAR) (AA 1-1226) protein (Strep Tag)

Crystallography grade ADAR 宿主: 人宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB

Adenosine Deaminase, RNA-Specific (ADAR) (AA 1-1178) protein (Strep Tag)

Crystallography grade ADAR 宿主: 小鼠宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB

Adenosine Deaminase, RNA-Specific (ADAR) (AA 1-176), (partial) protein (GST tag)

ADAR 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS

Adenosine Deaminase, RNA-Specific (ADAR) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)

ADAR 宿主: 人宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

说明: The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.
限制: 仅限研究用

状态: Lyophilized
浓度: 0.2-2 mg/mL
缓冲液: Tris-based buffer, 50 % glycerol
注意事项: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
储存条件: -20 °C
储存方法: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

Patterson, Samuel: "Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase." in: Molecular and cellular biology, Vol. 15, Issue 10, pp. 5376-88, (1995) (PubMed).

Kim, Wang, Sanford, Zeng, Nishikura: "Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 24, pp. 11457-61, (1994) (PubMed).

抗原: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))
别名: Double-stranded RNA-specific adenosine deaminase protein (ADAR 产品)
别名: red1 Protein, drada Protein, wu:fc22a02 Protein, adar1 Protein, dsRAD Protein, dsRAD-1 Protein, ADAR Protein, ADAR1 Protein, CG12598 Protein, Dmel\\CG12598 Protein, EG:BACN35H14.1 Protein, adar Protein, adr Protein, cg12598 Protein, dADAR Protein, dAdar Protein, hypnos-2 Protein, NV18763 Protein, AGS6 Protein, DRADA Protein, DSH Protein, DSRAD Protein, G1P1 Protein, IFI-4 Protein, IFI4 Protein, K88DSRBP Protein, P136 Protein, AV242451 Protein, Adar1 Protein, mZaADAR Protein, adenosine deaminase, RNA-specific Protein, adenosine deaminase, RNA-specific S homeolog Protein, adenosine deaminase, RNA specific Protein, Adenosine deaminase acting on RNA Protein, adenosine deaminase acting on RNA Protein, double-stranded RNA-specific editase 1 Protein, adar Protein, adar.S Protein, ADAR Protein, Adar Protein, CpipJ_CPIJ011849 Protein, LOC100114127 Protein
背景: Converts multiple adenosines to inosines and creates I/U mismatched base pairs in double-helical RNA substrates without apparent sequence specificity. Has been found to modify more frequently adenosines in AU-rich regions, probably due to the relative ease of melting A/U base pairs as compared to G/C pairs. Functions to modify viral RNA genomes and may be responsible for hypermutation of certain negative-stranded viruses. Edits the messenger RNAs for glutamate receptor (GLUR) subunits by site-selective adenosine deamination. Produces low-level editing at the GLUR-B Q/R site, but edits efficiently at the R/G site and HOTSPOT1. Binds to short interfering RNAs (siRNA) without editing them and suppresses siRNA-mediated RNA interference. Binds to ILF3/NF90 and up-regulates ILF3-mediated gene expression.
分子量: 47 kD
UniProt: P55265
途径: Protein targeting to Nucleus

ADAR Protein (AA 1-176, partial) (His-SUMO Tag)

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