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Alfa-1 Antitrypsin 蛋白

宿主: 人 宿主: Rice (Oryza sativa) Recombinant > 95 % , SDS Page
产品编号 ABIN1042573
发货至: 中国
  • 抗原
    Alfa-1 Antitrypsin
    蛋白类型
    Recombinant
    宿主
    资源
    • 1
    Rice (Oryza sativa)
    产品特性
    Activity: 3-5mg OsrAATwill inhibit 1mg PPE with an activity of 10.8 units per mg protein
    Formulation: Lyophilized from a 200 myL sterile-filtered solution added Osr HSA for protection.
    纯度
    > 95 % , SDS Page
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS pH7.0
    储存条件
    -20 °C
  • Zhang, Shi, Jiang, Stupak, Ou, Qiu, An, Li, Yang: "Expression and characterization of recombinant human alpha-antitrypsin in transgenic rice seed." in: Journal of biotechnology, Vol. 164, Issue 2, pp. 300-8, (2013) (PubMed).

  • 抗原
    Alfa-1 Antitrypsin
    别名
    A1A Protein, A1AT Protein, AAT Protein, PI Protein, PI1 Protein, PRO2275 Protein, alpha1AT Protein, serpin family A member 1 Protein, SERPINA1 Protein
    背景
    OsrAAT is a Human Recombinant protein produced in Rice, which is a single, non-glycosylated polypeptidechain containing 384 amino acids and has a molecular mass of 43.1 kDa. OsrAAT is a serine protease inhibitor which its targets include elastase, plasmin, collagenase, thrombin, leucocytic proteases, trypsin, chymotrypsin, and plasminogen activator. In its absence, neutrophil elastase is free to break down elastin, which contributes to the elasticity of the lungs, resulting in respiratory complications such as emphysema, or COPD (chronic obstructive pulmonary disease) in adults and cirrhosis in adults or children. The OsrAAT protein is purified by chromatographic techniques.
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