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|抗原||Interleukin 13 (IL13) 抗体|
|标记||This IL-13 antibody is un-conjugated 其他选择|
Blocking Antibody (Inhibition), ELISA, Western Blotting (WB)
IL-13抗体详情IL-13目标详情 使用细节 贮存及处理 图像
|免疫原||IL13 antibody was raised in rabbit using highly pure recombinant murine IL-13 as the immunogen.|
|Plasmids, Primers & others|
IL-13目标详情IL-13抗体详情 使用细节 贮存及处理 图像 回页首
|别名||IL13 (IL13 Antibody 摘要)|
|背景||IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL13 in mice resulted in impaired Th2 cell development and indicated an important role for IL13 in the expulsion of gastrointestinal parasites. IL13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL1beta, TNF-alpha, IL6 and IL8. IL13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL13 activity inhibits the pathophysiology of asthma. Human and Mouse IL13 is cross-species reactive.|
|分子量||12.3 kDa (predicted detection band MW)|
|途径||JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport|
使用细节IL-13抗体详情 IL-13目标详情 贮存及处理 图像 回页首
ELISA: 0.5-2 µg/mL, Inhibition: 0.08-0.1 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.
贮存及处理IL-13抗体详情 IL-13目标详情 使用细节 图像 回页首
|缓冲液||Lyophilized from PBS, pH 7.2.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|储存方法||Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.|