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IKZF1 蛋白

(IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

This gene encodes a transcription factor that belongs to the family of zinc-finger DNA binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. All isoforms share a common C-terminal domain, which contains two zinc finger motifs that are required for hetero- or homodimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-terminal zinc finger motifs that bind DNA and contain the nuclear localization signal, resulting in members with and without DNA-binding properties. Only few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding to a specific core DNA sequence element in the promoters of target genes. The non-DNA-binding isoforms are largely found in the cytoplasm, and thought to function as dominant negative factors. Overexpression of some dominant-negative isoforms have been associated with B-cell malignancies, such as acute lymphoblastic leukemia (ALL). [provided by RefSeq, May 2011].

recommended

IKZF1 Protein (AA 1-477) (GST tag) (ABIN1307650)

IKZF1 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

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recommended

IKZF1 Protein (AA 1-519) (His tag) (ABIN7123400)

IKZF1 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB

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recommended

IKZF1 Protein (AA 1-519) (Strep Tag) (ABIN3093023)

Crystallography grade IKZF1 宿主: 人宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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IKZF1 蛋白 by Grade

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IKZF1 蛋白 by Origin

Find IKZF1 蛋白 for a variety of species such as anti-Human IKZF1, anti-Mouse IKZF1. The species listed below are among those available. Click on a link to go to the corresponding products.

IKZF1 蛋白 by Source

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IKZF1 蛋白 by 蛋白类型

Here you can find IKZF1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

IKZF1 蛋白 by 应用范围

Find IKZF1 蛋白 validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular IKZF1 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

IKZF1 Protein (AA 1-477) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1307650

Quantity 10 μg

Datasheet Datasheet

IKZF1 Protein (AA 1-519) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7123400

Quantity 50 μg

Datasheet Datasheet

IKZF1 Protein (AA 1-519) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3093023

Quantity 1 mg

Datasheet Datasheet

IKZF1 Protein (AA 1-517) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3134815

Quantity 1 mg

Datasheet Datasheet

IKZF1 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2723364

Quantity 20 μg

Datasheet Datasheet

Aliases for IKZF1 蛋白

IKAROS family zinc finger 1 (IKZF1) 蛋白
IKAROS family zinc finger 1 (Ikzf1) 蛋白
IKAROS family zinc finger 1 (Ikaros) (ikzf1) 蛋白
IKAROS family zinc finger 1 (ikzf1) 蛋白
5832432G11Rik 蛋白
hIk-1 蛋白
hik-1 蛋白
hlk-1 蛋白
Hs.54452 蛋白
hs.54452 蛋白
IK1 蛋白
ik1 蛋白
IKAROS 蛋白
ikaros 蛋白
Ikaros 蛋白
ikzf1 蛋白
LyF-1 蛋白
LYF1 蛋白
lyf1 蛋白
MGC108252 蛋白
mKIAA4227 蛋白
PRO0758 蛋白
pro0758 蛋白
RGD1562979 蛋白
Zfpn1a1 蛋白
ZNFN1A1 蛋白
znfn1a1 蛋白
Znfn1a1 蛋白

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IKZF1 蛋白 by Grade

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IKZF1 蛋白 by Source

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IKZF1 蛋白 by 应用范围

Popular IKZF1 蛋白

Aliases for IKZF1 蛋白

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