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抗Human BCLAF1 抗体:
抗Mouse (Murine) BCLAF1 抗体:
抗Rat (Rattus) BCLAF1 抗体:
Human Polyclonal BCLAF1 Primary Antibody for ICC, IF - ABIN151225
Liu, Lu, Miki, Yoshida: Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage. in Molecular and cellular biology 2007
Show all 4 Pubmed References
Human Monoclonal BCLAF1 Primary Antibody for IF, WB - ABIN968645
Kasof, Goyal, White: Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins. in Molecular and cellular biology 1999
Results indicate a role for the RNA processing factors THRAP3 (显示 THRAP3 抗体) and BCLAF1 in the regulation of the cellular DNA damage response (DDR (显示 DDR1 抗体)) pathway.
findings link treatment responsiveness to re-instatement of miR (显示 MLXIP 抗体)-194-5p/BCLAF1 balance
SMYD3 (显示 SMYD3 抗体) physically interacts with the promoter of BCLAF1 and upregulates its expression by accumulating di- and trimethylation of H3K4 at the BCLAF1 locus. BCLAF1 depletion inhibits SMYD3 (显示 SMYD3 抗体)-induced autophagy.
The Bclaf1 can interact with the leucine zipper region of C/EBPbeta (显示 CEBPB 抗体) and cooperate with C/EBPbeta (显示 CEBPB 抗体) to upregulate IL-8 (显示 IL8 抗体).
both cytoplasmic BCLAF1 expression and nuclear BCLAF1 expression are increased in post-neoadjuvant therapy rectal cancer, and that negative and weak nuclear BCLAF1 expression are independently associated with a poor prognosis
SRSF10 (显示 SRSF10 抗体) is a key regulator of BCLAF1 pre-mRNA splicing and the maintenance of oncogenic features in human colon cancer cells
findings showed that FXR1P (显示 FXR1 抗体) interacts with BTF in vivo and proved that FXR1P (显示 FXR1 抗体) and BTF can co-localize mainly in the cytoplasm around the nucleus
BTF has functions distinct from TRAP150 (显示 THRAP3 抗体) in regulating the subcellular distribution of mRNAs in human cells.
BCLAF1 co-localized with gammaH2AX (显示 H2AFX 抗体) foci in nuclei and stabilized the Ku70 (显示 XRCC6 抗体)/DNA-PKcs (显示 PRKDC 抗体) complex therein, facilitating non-homologous end joining (NHEJ)-based DSB repair in surviving cells.
In the absence of BclAF1 neutralization, viral gene expression and replication are inhibited. These data identify two temporally and mechanistically distinct functions used by human cytomegalovirus to down-regulate a cellular antiviral protein
Constitutive expression of the anti-apoptotic molecule Bfl1 (显示 BCL2A1 抗体) (A1) in murine vascular Endothelial Cells leads to prolonged allograft survival due to modifying inflammation.
Bclaf1 facilitates the differentiation of early retinal precursors into retinal ganglion cells, amacrine cells, and horizontal cells rather than into cone photoreceptors.
Sirt1 (显示 SIRT1 抗体) negatively regulates T cell activation via H3K56 deacetylation at the promoter region to inhibit transcription of Bclaf1
Bclaf1 expression was found to be strongly upregulated during the saccular stage of murine embryonic lung development and was dispensable for thymocyte development.
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
BCL2-associated transcription factor 1
, bcl-2-associated transcription factor 1
, mitochondrial fission regulator 2
, protein FAM54A