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PUMA 抗体

(BCL2 Binding Component 3 (BBC3))
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011].
PUMA 抗体  (C-Term) PUMA 抗体  (C-Term) PUMA 抗体 (C-Term) (ABIN361748)

BBC3 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated

PUMA 抗体 PUMA 抗体 PUMA 抗体 (ABIN1678790)

BBC3 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

PUMA 抗体  (AA 131-180) PUMA 抗体  (AA 131-180) PUMA 抗体 (AA 131-180) (ABIN731528)

BBC3 适用: 人, 大鼠, Pig WB, ELISA, FACS, IP, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

PUMA 抗体 by Grade

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PUMA 抗体 by 适用

Find PUMA 抗体 for a variety of species such as anti-Human PUMA, anti-Rat PUMA, anti-Mouse PUMA. The species listed below are among those available. Click on a link to go to the corresponding products.

PUMA 抗体 by 应用范围

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PUMA 抗体 by 抗原表位

Find PUMA 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PUMA 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PUMA 抗体. Click on a link to go to the corresponding products.

PUMA 抗体 by 克隆

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PUMA 抗体 by 标记

Find PUMA 抗体 with a specific conjugate such as Biotin, FITC, PE. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PUMA 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ICC, IF
Validations
  • (6)
Cat. No. ABIN361748
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN1678790
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Pig, Rat
Application WB, ELISA, FACS, IP, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (3)
  • (4)
Cat. No. ABIN731528
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF, FACS
Validations
  • (6)
Cat. No. ABIN3030112
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ICC, IF
Validations
  • (4)
Cat. No. ABIN2485958
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ICC, IF
Validations
  • (4)
Cat. No. ABIN2485953
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ICC, IF
Validations
  • (4)
Cat. No. ABIN2485945
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ICC, IF
Validations
  • (4)
Cat. No. ABIN2485947
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ICC, IF
Validations
  • (4)
Cat. No. ABIN2485944
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (3)
Cat. No. ABIN361754
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ICC, IF
Validations
  • (4)
Cat. No. ABIN2485956
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ICC, IF
Validations
  • (4)
Cat. No. ABIN2485955
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ICC, IF
Validations
  • (4)
Cat. No. ABIN2485952
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ICC, IF
Validations
  • (4)
Cat. No. ABIN2485954
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ICC, IF
Validations
  • (4)
Cat. No. ABIN2485959
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PUMA 抗体

Kim, Yu, Chen, Xu, Wu, Todorova, Tang, Feng, Jiang, He, Chen, Fu, Xu: "Wild-Type p53 Promotes Cancer Metabolic Switch by Inducing PUMA-Dependent Suppression of Oxidative Phosphorylation." in: Cancer cell, Vol. 35, Issue 2, pp. 191-203.e8, (2019) (PubMed).

Choi, Koh, Cho, Kim, Kim, Hur: "Temporal and differential regulation of KAISO-controlled transcription by phosphorylated and acetylated p53 highlights a crucial regulatory role of apoptosis." in: The Journal of biological chemistry, Vol. 294, Issue 35, pp. 12957-12974, (2019) (PubMed).

Zhang, Li, Wang, Li, Shi, Kan, Pang: "Inhibition of REST Suppresses Proliferation and Migration in Glioblastoma Cells." in: International journal of molecular sciences, Vol. 17, Issue 5, (2017) (PubMed).

Liao, Chu, Hu, Merkin, Chen, Liu, Degenhardt, White, Ryazanov: "Paradoxical Roles of Elongation Factor-2 Kinase in Stem Cell Survival." in: The Journal of biological chemistry, Vol. 291, Issue 37, pp. 19545-57, (2016) (PubMed).

Su, Shi, Yan, Xi, Su: "Anticancer bioactive peptides suppress human colorectal tumor cell growth and induce apoptosis via modulating the PARP-p53-Mcl-1 signaling pathway." in: Acta pharmacologica Sinica, Vol. 36, Issue 12, pp. 1514-9, (2016) (PubMed).

Vesela, Matalova: "Detection of Bim and Puma in mouse hair follicles using immunofluorescence and TUNEL assay double staining." in: Biotechnic & histochemistry : official publication of the Biological Stain Commission, pp. 1-7, (2015) (PubMed).

Long, Schoonen, Graczyk, OPrey, Ryan: "p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death." in: Oncogene, (2015) (PubMed).

Hui, Yuan, Ren, Jiang: "Nerve growth factor reduces apoptotic cell death in rat facial motor neurons after facial nerve injury." in: Neurosciences (Riyadh, Saudi Arabia), Vol. 20, Issue 1, pp. 65-8, (2015) (PubMed).

Qiu, Cai, Gao, Gu, Liu: "A small peptide derived from p53 linker region can resume the apoptotic activity of p53 by sequestering iASPP with p53." in: Cancer letters, Vol. 356, Issue 2 Pt B, pp. 910-7, (2014) (PubMed).

Sale, Cook: "The BH3 mimetic ABT-263 synergizes with the MEK1/2 inhibitor selumetinib/AZD6244 to promote BIM-dependent tumour cell death and inhibit acquired resistance." in: The Biochemical journal, Vol. 450, Issue 2, pp. 285-94, (2013) (PubMed).

Aliases for PUMA 抗体

BCL2 binding component 3 (BBC3) 抗体
Bcl-2 binding component 3 (Bbc3) 抗体
BCL2 binding component 3 (Bbc3) 抗体
BCL2 binding component 3 (bbc3) 抗体
BBC3 抗体
JFY-1 抗体
JFY1 抗体
Puma 抗体
PUMA 抗体
PUMA/JFY1 抗体
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