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PHLPP2 蛋白

(PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2))
Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser- 657' of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Inhibits cancer cell proliferation and may act as a tumor suppressor.
PHLPP2 Protein (AA 766-1043) (His tag) PHLPP2 Protein (AA 766-1043) (His tag) PHLPP2 Protein (AA 766-1043) (His tag) (ABIN7124383)

PHLPP2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

PHLPP2 Protein (AA 1-1323) (His tag) PHLPP2 Protein (AA 1-1323) (His tag) PHLPP2 Protein (AA 1-1323) (His tag) (ABIN3094545)

Crystallography grade PHLPP2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys

PHLPP2 Protein (AA 1-1320) (His tag) PHLPP2 Protein (AA 1-1320) (His tag) PHLPP2 Protein (AA 1-1320) (His tag) (ABIN3136302)

Crystallography grade PHLPP2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys

PHLPP2 蛋白 by Grade

Find PHLPP2 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PHLPP2 蛋白 by Origin

Find PHLPP2 蛋白 for a variety of species such as anti-Human PHLPP2, anti-Mouse PHLPP2. The species listed below are among those available. Click on a link to go to the corresponding products.

PHLPP2 蛋白 by Source

Here you will find PHLPP2 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

PHLPP2 蛋白 by 蛋白类型

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PHLPP2 蛋白 by 应用范围

Find PHLPP2 蛋白 validated for a specific application such as WB, ELISA, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular PHLPP2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124383
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094545
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136302
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2728850
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6700357
Quantity 50 μg
Datasheet Datasheet

Aliases for PHLPP2 蛋白

PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2) 蛋白
PH domain and leucine rich repeat protein phosphatase 2 S homeolog (phlpp2.S) 蛋白
PH domain and leucine rich repeat protein phosphatase 2 (phlpp2) 蛋白
PH domain and leucine rich repeat protein phosphatase 2 (Phlpp2) 蛋白
AI481772 蛋白
C130044A18Rik 蛋白
PHLPPL 蛋白
phlppl 蛋白
Phlppl 蛋白
RGD1562857 蛋白
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