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PDK3 抗体

(Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
PDK3 抗体  (AA 174-263) PDK3 抗体  (AA 174-263) PDK3 抗体 (AA 174-263) (ABIN562161)

PDK3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated

PDK3 抗体 PDK3 抗体 PDK3 抗体 (ABIN7075334)

PDK3 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

PDK3 抗体  (AA 174-263) PDK3 抗体  (AA 174-263) PDK3 抗体 (AA 174-263) (ABIN518759)

PDK3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A1 unconjugated

PDK3 抗体 by 适用

Find PDK3 抗体 for a variety of species such as anti-Human PDK3, anti-Mouse PDK3, anti-Rat PDK3. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find PDK3 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

PDK3 抗体 by 抗体来源

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PDK3 抗体 by 抗原表位

Find PDK3 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PDK3 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PDK3 抗体. Click on a link to go to the corresponding products.

PDK3 抗体 by 克隆

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PDK3 抗体 by 标记

Find PDK3 抗体 with a specific conjugate such as FITC, Biotin, APC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PDK3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
  • (4)
Cat. No. ABIN562161
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (3)
Cat. No. ABIN7075334
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN518759
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7142007
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN545487
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p), ICC, IF
Validations
  • (2)
Cat. No. ABIN2855802
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
  • (2)
Cat. No. ABIN391038
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (1)
  • (2)
Cat. No. ABIN652286
Quantity 400 μL
Datasheet Datasheet

Application WB, IHC
Validations
  • (3)
Cat. No. ABIN2782501
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7176880
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IP
Validations
  • (1)
Cat. No. ABIN518758
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7256140
Quantity 200 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6743407
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6738214
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN5014242
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PDK3 抗体

Hou, Zhang, Han, Ge, Ma, Zhang, Moley, Schedl, Wang: "Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation." in: Journal of cell science, Vol. 128, Issue 13, pp. 2319-29, (2015) (PubMed).

Ho, Coomber: "Pyruvate dehydrogenase kinase expression and metabolic changes following dichloroacetate exposure in anoxic human colorectal cancer cells." in: Experimental cell research, Vol. 331, Issue 1, pp. 73-81, (2015) (PubMed).

Shimura, Nakai, Jiao, Osanai, Kashikura, Endo, Soga, Goda, Minamisawa: "Metabolomic profiling analysis reveals chamber-dependent metabolite patterns in the mouse heart." in: American journal of physiology. Heart and circulatory physiology, Vol. 305, Issue 4, pp. H494-505, (2013) (PubMed).

Hwang, Wu, Harris: "Additive effects of clofibric acid and pyruvate dehydrogenase kinase isoenzyme 4 (PDK4) deficiency on hepatic steatosis in mice fed a high saturated fat diet." in: The FEBS journal, Vol. 279, Issue 10, pp. 1883-93, (2012) (PubMed).

Halim, Mcfate, Mohyeldin, Okagaki, Korotchkina, Patel, Jeoung, Harris, Schell, Verma: "Phosphorylation status of pyruvate dehydrogenase distinguishes metabolic phenotypes of cultured rat brain astrocytes and neurons." in: Glia, Vol. 58, Issue 10, pp. 1168-76, (2010) (PubMed).

Jeoung, Harris: "Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice." in: American journal of physiology. Endocrinology and metabolism, Vol. 295, Issue 1, pp. E46-54, (2008) (PubMed).

Lu, Lin, Chen, Lai, Tsai: "Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance." in: The Journal of biological chemistry, Vol. 283, Issue 42, pp. 28106-14, (2008) (PubMed).

McFate, Mohyeldin, Lu, Thakar, Henriques, Halim, Wu, Schell, Tsang, Teahan, Zhou, Califano, Jeoung, Harris, Verma: "Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells." in: The Journal of biological chemistry, Vol. 283, Issue 33, pp. 22700-8, (2008) (PubMed).

Xu, Han, Epstein, Liu: "Regulation of PDK mRNA by high fatty acid and glucose in pancreatic islets." in: Biochemical and biophysical research communications, Vol. 344, Issue 3, pp. 827-33, (2006) (PubMed).

Aliases for PDK3 抗体

pyruvate dehydrogenase kinase 3 (PDK3) 抗体
pyruvate dehydrogenase kinase 3 (Pdk3) 抗体
pyruvate dehydrogenase kinase, isozyme 3a (pdk3a) 抗体
pyruvate dehydrogenase kinase 3 (pdk3) 抗体
pyruvate dehydrogenase kinase, isoenzyme 3 (Pdk3) 抗体
fragile site, 5-azacytidine type, common, fra(1)(q12) (FRA1J) 抗体
pyruvate dehydrogenase kinase, isozyme 3b (pdk3b) 抗体
2610001M10Rik 抗体
AI035637 抗体
pdk3 抗体
PDK3 抗体
zgc:158702 抗体
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