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NEAT1 was potentially communicated with mTOR (显示 FRAP1 蛋白) signaling target protein mLST8 via the association with miR (显示 MLXIP 蛋白)-181b in type 2 diabetes mellitus.
Autophagy regulates c-MET phosphorylation via an mTORC2 (显示 CRTC2 蛋白)-dependent mechanism.
Data suggest MTMR3 (显示 MTMR3 蛋白) has multiple functions in regulation of autophagy; one mechanism appears to be direct interaction between MTMR3 (显示 MTMR3 蛋白) and mTORC1 (MTOR (显示 FRAP1 蛋白), mLST8, raptor (显示 RPTOR 蛋白)) which inhibits phosphorylation activity of mTORC1; MTMR3 (显示 MTMR3 蛋白) is localized to Golgi apparatus.
MLST8 upregulation may contribute to tumor progression.
Amino acids promote mTORC1 activation without altering Rag GTP (显示 AK3 蛋白) charging.
MLST8 polymorphism is associated with gastric cancer.
The results obtained indicate that mLST8 bridges between CAD and mTOR (显示 FRAP1 蛋白), and plays a role in the signaling mechanism where CAD is regulated in the mTOR (显示 FRAP1 蛋白) pathway through the association with mLST8.
An essential role of mTORC1 in autophagy inhibition in cell-free system in which, membrane association of Barkor/Atg14(L), a specific autophagosome-binding protein, is suppressed by cytosol from nutrient-rich medium, is shown.
show that E2F1 (显示 E2F1 蛋白) is capable of inducing growth by regulating mTORC1 activity
Adiponectin induces vascular smooth muscle cell differentiation via repression of mammalian target of rapamycin (显示 FRAP1 蛋白) complex 1 and FoxO4 (显示 FOXO4 蛋白)
the crosstalk between AMPK (显示 PRKAA1 蛋白) and mTORC1 signaling is a highly regulated way to control changes in muscle growth and metabolic rate imposed by external cues.
The mutant, Gbeta1(W332A) protein, although inactive, retains its ability to bind Kir3 and prevents the wild type Gbeta (显示 SUCLG2 蛋白) from activating the channel.
cytosolic protein similar to an insulin receptor
Protein LTS8 homolog
, TORC subunit lst8
, protein GbetaL
, target of rapamycin complex subunit lst8
, TORC subunit LST8
, mammalian lethal with SEC13 protein 8
, target of rapamycin complex subunit LST8
, transducin (beta)-like 4
, G beta-like protein