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Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12) (N-Term) Peptide

PSMD12 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN982377
发货至: 中国
  • 抗原 See all PSMD12 products
    PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
    蛋白结构域
    N-Term
    宿主
    资源
    • 4
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    MADGGSERAD GRIVKMEVDY SATVDQRLPE CAKLAKEGRL QEVIETLLSL
    产品特性
    This is a synthetic peptide designed for use in combination with anti-PSMD12 Antibody(ARP57839_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
    别名
    wu:fb38a06 Peptide, wu:fc34f08 Peptide, wu:fc49f02 Peptide, PSMD12 Peptide, rpn5 Peptide, Rpn5 Peptide, p55 Peptide, 1500002F15Rik Peptide, AI480719 Peptide, P55 Peptide, proteasome 26S subunit, non-ATPase 12 Peptide, proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 Peptide, psmd12 Peptide, PSMD12 Peptide, Psmd12 Peptide
    背景
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3.

    Alias Symbols: MGC75406, p55, Rpn5

    Protein Interaction Partner: PSMD13,TRAF6,PAAF1,PSMD10,PSMD13,PSMD14,PSMD6,PSMD7,TRAF6,UCHL5,USP14,USP20

    Protein Size: 456
    分子量
    50 kDa
    基因ID
    5718
    NCBI登录号
    NM_002816, NP_002807
    UniProt
    O00232
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