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Plasminogen Activator, Tissue (PLAT) (Middle Region) Peptide

PLAT 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN981837
发货至: 中国
  • 抗原 See all PLAT products
    PLAT (Plasminogen Activator, Tissue (PLAT))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 1
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    TVILGRTYRV VPGEEEQKFE VEKYIVHKEF DDDTYDNDIA LLQLKSDSSR
    产品特性
    This is a synthetic peptide designed for use in combination with anti-PLAT Antibody(ARP57691_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    PLAT (Plasminogen Activator, Tissue (PLAT))
    别名
    T-PA Peptide, TPA Peptide, AU020998 Peptide, AW212668 Peptide, D8Ertd2e Peptide, tPA Peptide, PATISS Peptide, tpa Peptide, Plat Peptide, plat Peptide, t-pa Peptide, plasminogen activator, tissue type Peptide, plasminogen activator, tissue Peptide, chromosome 20 open reading frame 181 Peptide, plasminogen activator, tissue L homeolog Peptide, PLAT Peptide, Plat Peptide, plat Peptide, C20orf181 Peptide, plat.L Peptide
    背景
    This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

    Alias Symbols: DKFZp686I03148, T-PA, TPA

    Protein Interaction Partner: ANXA2,CALR,CKAP4,CLEC3B,F10,FGA,GRIN1,HMGB1,KRT8,LAMA1,LAMA3,LRP1,LRP1B,MAPK1,MAPK3,PLAT,PLAU,PLG,SERPINA5,SERPINE1,SERPING1,SERPINI1,SPARC,ANXA2,CALR,CLEC3B,F10,F2,FGA,FN1,HMGB1,KRT8,LAMA1,LAMA5,LRP1,PLAU,SERPINA5,SERPINE1,SERPINI1

    Protein Size: 516
    分子量
    53 kDa
    基因ID
    5327
    NCBI登录号
    NM_033011, NP_127509
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