Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (C-Term) Peptide
PICALM
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all PICALM products
- PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- DLDSSLANLV GNLGIGNGTT KNDVNWSQPG EKKLTGGSNW QPKVAPTTAW
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-PICALM Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))
- 别名
- LAP-3 Peptide, PEPS Peptide, CALM Peptide, CLTH Peptide, LAP Peptide, PAP180 Peptide, fit-1 Peptide, fit1 Peptide, mKIAA4114 Peptide, Calm Peptide, leucine aminopeptidase 3 Peptide, phosphatidylinositol binding clathrin assembly protein Peptide, si:ch211-200p22.4 Peptide, LAP3 Peptide, PICALM Peptide, Picalm Peptide, si:ch211-200p22.4 Peptide
- 背景
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This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10,11)(p13,q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease.
Alias Symbols: CALM, CLTH, LAP
Protein Interaction Partner: AP2A1,CASP3,CASP8,CLTC,CLTCL1,DDIT3,EHD2,PLCG1,CLTC,DDIT3,PLCG1
Protein Size: 551 - 分子量
- 60 kDa
- 基因ID
- 8301
- NCBI登录号
- NM_001206947, NP_001193876
- UniProt
- E9PN05
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