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Protein Inhibitor of Activated STAT, 1 (PIAS1) (N-Term) Peptide

PIAS1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN981725
发货至: 中国
  • 抗原 See all PIAS1 products
    PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))
    蛋白结构域
    N-Term
    宿主
    资源
    • 2
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-PIAS1 antibody (Catalog #: ARP39231_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))
    别名
    2900068C24Rik Peptide, Ddxbp1 Peptide, GBP Peptide, DDXBP1 Peptide, GU/RH-II Peptide, ZMIZ3 Peptide, ddxbp1 Peptide, gbp Peptide, pias Peptide, pias1-A Peptide, xPAIS1 Peptide, xPIAS1 Peptide, zmiz3 Peptide, protein inhibitor of activated STAT 1 Peptide, protein inhibitor of activated STAT, 1 Peptide, protein inhibitor of activated STAT, 1a Peptide, protein inhibitor of activated STAT 1 L homeolog Peptide, PIAS1 Peptide, Pias1 Peptide, pias1a Peptide, pias1.L Peptide
    背景
    PIAS1 is a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis.This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: DDXBP1, GBP, GU/RH-II, MGC141878, MGC141879, ZMIZ3

    Protein Interaction Partner: CEBPA,CEBPE,CASP8,CSRP2,ESR1,HTNVsSgp1,SUMO1,TP53,UBE2I,AR,AXIN1,CASP8,CEBPA,CEBPE,CHUK,CREBBP,CSRP2,DCLRE1A,DDX21,DNM1,DNMT3A,ELK3,ESR1,ESR2,GATA4,GRM8,JUN,MBD1,MDM2,MSX1,NIN,NR2F2,NR3C2,NR5A1,PGR,PIAS1,PIAS2,PIAS4,PRPF40A,PTK2,PTPN1,RELA,SATB2,SERBP1,SKIL,SMAD1,SMAD4,SMAD7,SNIP1,SP3,STAT1,SUFU,SUMO1,TBP,TP53,TP73,UBE2I,ZNF76,AKT1,AR,CSRP2,DNMT3A,MX1,SIAH1,SIAH2,SP3,STAB2,STAT1,SUMO1,SUMO2,TP53,UBE2I,ZMIZ2

    Protein Size: 651
    分子量
    72 kDa
    基因ID
    8554
    NCBI登录号
    NM_016166, NP_057250
    UniProt
    O75925
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