Platelet Derived Growth Factor Subunit B (PDGFB) (N-Term) Peptide
PDGFB
适用: 人
宿主: 合成
BP, IHC, WB
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- 抗原 See all PDGFB products
- PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-PDGFB antibody (Catalog #: ARP58509_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))
- 别名
- PDGF-2 Peptide, PDGF2 Peptide, SIS Peptide, SSV Peptide, c-sis Peptide, pdgf2 Peptide, sis Peptide, si:ch211-79m20.1 Peptide, si:dkey-261d11.1 Peptide, PDGF-B Peptide, Sis Peptide, platelet derived growth factor subunit B Peptide, platelet-derived growth factor beta polypeptide Peptide, platelet derived growth factor subunit B S homeolog Peptide, platelet-derived growth factor beta polypeptide a Peptide, platelet derived growth factor, B polypeptide Peptide, PDGFB Peptide, pdgfb.S Peptide, pdgfba Peptide, Pdgfb Peptide
- 背景
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PDGFB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor.The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two splice variants have been identified for this gene.
Alias Symbols: FLJ12858, PDGF2, SIS, SSV, c-sis
Protein Interaction Partner: A2M,ART1,COL1A1,HRAS,HSPG2,LRP1,PDAP1,PDGFB,PDGFRA,PDGFRB,THBS1,HSPG2,LRP1,PDAP1,PDGFB,PDGFRA,SPARC,THBS1
Protein Size: 241 - 分子量
- 27 kDa
- 基因ID
- 5155
- NCBI登录号
- NM_002608, NP_002599
- UniProt
- P01127
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