Membrane Metallo-Endopeptidase (MME) (C-Term) Peptide
MME
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all MME products
- MME (Membrane Metallo-Endopeptidase (MME))
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- EYAVNSIKTD VHSPGNFRII GTLQNSAEFS EAFHCRKNSY MNPEKKCRVW
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-MME Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- MME (Membrane Metallo-Endopeptidase (MME))
- 别名
- CALLA Peptide, CD10 Peptide, NEP Peptide, SFE Peptide, 6030454K05Rik Peptide, C85356 Peptide, Nep Peptide, neprilysin Peptide, membrane metalloendopeptidase Peptide, membrane metallo endopeptidase Peptide, membrane metallo-endopeptidase Peptide, MME Peptide, Mme Peptide
- 物质类
- Chemical
- 背景
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This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts.
Alias Symbols: CALLA, CD10, DKFZp686O16152, MGC126681, MGC126707, NEP, SFE
Protein Interaction Partner: ADCYAP1,ADM,CSNK2B,EDN1,EDN2,GAST,LYN,NDRG1,NPPA,NPPC,PIK3CB,PIK3R1,SHC1,VIP,ALDH3A2,ARL1,ARMC10,ATP12A,ATP5J2,CD4,CDK5RAP3,CLEC4M,CPSF6,CSNK2A1,DNAJB12,EEF1A1,FAAH,FAHD1,FAM83F,FECH,FLOT2,FOLH1,HIST1H2AG,HSPA1A,HSPA4,HSPA8,HSPB1,IMPDH2,INPP5D,IRAK2,ITFG3,KBTBD3,KRT10,LAMTOR1,LMNA,LONP1,LYN,METTL7A,MME,MRPL44,MRPS25,MRVI1,MTDH,MTHFD1,MYH9,NDUFA10,NDUFA9,NDUFB4,NNT,NOLC1,NUCKS1,OPA1,PCNA,PDIA5,POTEI,RAP2B,RBM39,RGPD6,RPL30,RPS10,RPS23,RUVBL1,RUVBL2,SDF4,SLC16A1,SLC9A3R1,SRSF11,SSR4,TM9SF1,TNPO1,TUBB8,UBAC2,UTRN,VDAC2,XRCC5,ZMPSTE24
Protein Size: 750 - 分子量
- 83 kDa
- 基因ID
- 4311
- NCBI登录号
- NM_007287, NP_009218
- UniProt
- P08473
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