LIM Homeobox Transcription Factor 1, alpha (LMX1A) Peptide
LMX1A
适用: 人
宿主: 合成
BP, WB, IHC
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- 抗原 See all LMX1A products
- LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-LMX1A antibody (Catalog #: ARP31999_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))
- 别名
- Lmx1.1 Peptide, dr Peptide, dreher Peptide, sst Peptide, LMX1 Peptide, LMX1.1 Peptide, si:ch211-260g14.3 Peptide, LIM homeobox transcription factor 1 alpha Peptide, LIM homeobox transcription factor 1, alpha Peptide, Lmx1a Peptide, LMX1A Peptide, lmx1a Peptide
- 背景
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Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS, MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin. Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS, MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin (German et al., 1994 [PubMed 7698771]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-199 AL160058.8 14249-14447 c 200-2447 AK127724.1 362-2609 2448-3382 AL390730.12 9415-10349 c
Alias Symbols: LMX-1, LMX1, LMX1.1, MGC87616
Protein Interaction Partner: BMPR2,ISL1,LDB1,ISL1,LHX3,LMX1A,TCF3
Protein Size: 382 - 分子量
- 43 kDa
- 基因ID
- 4009
- NCBI登录号
- NM_177398, NP_796372
- UniProt
- Q8TE12
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