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LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) (C-Term) Peptide

LIMS1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN979328
发货至: 中国
  • 抗原 See all LIMS1 products
    LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
    蛋白结构域
    C-Term
    宿主
    资源
    • 1
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    VNCFACSTCN TKLTLKNKFV EFDMKPVCKK CYEKFPLELK KRLKKLAETL
    产品特性
    This is a synthetic peptide designed for use in combination with anti-LIMS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
    别名
    PINCH Peptide, PINCH-1 Peptide, PINCH1 Peptide, Pinch1 Peptide, RGD1560732 Peptide, LIMS3 Peptide, LIMS3L Peptide, 2310016J22Rik Peptide, 4921524A02Rik Peptide, AI507642 Peptide, AU021743 Peptide, AW551584 Peptide, C430041B13Rik Peptide, Lims1l Peptide, LIM zinc finger domain containing 1 Peptide, LIM and senescent cell antigen-like domains 1 Peptide, LIMS1 Peptide, Lims1 Peptide
    背景
    The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: PINCH, PINCH1

    Protein Interaction Partner: ILK,NCK2,TMSB4X,EHMT2,ILK,LPXN,NCK2,PARVA,RBBP8,RSU1,SMURF1,TGFBR1,TMSB4X,ACP6,EHMT2,ILK,LPXN,NCK2,RBBP8,STK11,UBC

    Protein Size: 387
    分子量
    44 kDa
    基因ID
    3987
    NCBI登录号
    NM_001193485, NP_001180414
    UniProt
    B7Z7R3
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