Growth Factor Receptor-Bound Protein 2 (GRB2) (N-Term) Peptide
GRB2
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all GRB2 products
- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- AKYDFKATAD DELSFKRGDI LKVLNEECDQ NWYKAELNGK DGFIPKNYIE
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-GRB2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
- 背景
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The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2
Protein Interaction Partner: ADRB1,BCR,BCR,CBL,CHRM4,DRD3,DRD4,DRD4,DRD4,EGFR,EGFR,FASLG,HCVgp1,HTT,KHDRBS1,KIT,KIT,MAP4K1,PAK1,PDE4D,PTK2,PTPN11,RHOU,SH3KBP1,SHC1,SHC1,SOCS1,SOS1,USP6NL,VAV1,ABL1,ADA,ADAM12,ADAM15,ADRB1,ADRB2,ALOX5,ANXA2,APP,AXL,BCAR1,BCL2A1,BCR,BLNK,CALD1,CBLB,CBLC
Protein Size: 217 - 分子量
- 24 kDa
- 基因ID
- 2885
- NCBI登录号
- NM_002086, NP_002077
- UniProt
- P62993
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