This is a synthetic peptide designed for use in combination with anti-DOT1L antibody (Catalog #: ARP47938_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
DISC1
(Disrupted in Schizophrenia 1 (DISC1))
别名
DISC1 Peptide, C1orf136 Peptide, SCZD9 Peptide, disrupted in schizophrenia 1 Peptide, disrupted in schizophrenia 1 protein Peptide, disc1 Peptide, DISC1 Peptide, LOC100580606 Peptide, Disc1 Peptide
背景
DOT1L is a histone methyltransferase. It methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones.
Alias Symbols: DOT1, KIAA1814, KMT4, SCZD9, C1orf136
Protein Interaction Partner: ACTN2,ANKHD1,ATF4,ATF5,ATF7IP,EIF3H,ITSN1,MAP1A,NDEL1,PCNT,RANBP9,SPTBN4,TRAF3IP1,ACTN2,ATF4,ATF5,ATF7IP,CCDC141,CIT,DISC1,EIF3H,FEZ1,ITSN1,KCNQ5,MAP1A,NDEL1,PCNT,RANBP9,SPTBN4,SYNE1,TRAF3IP1,YWHAG,ACTN2,ATF4,ATF4,ATF5,ATF7IP,CCDC141,CEP290,CEP63,CIT,COL4A1,EIF3A,EIF3H,EPB49,FEZ1,GOLGA2,IMMT,ITSN1,KALRN,KATNAL1,KCNQ5,KIAA1377,MAP1A,MGAT3,MYO1A,NDE1,NDEL1,PPFIA4,RANBP9,RASSF7,SMARCE1,SPTAN1,SPTBN4,SYNE1,TRAF3IP1,YWHAG