Caspase 1 (CASP1) (Middle Region) Peptide
CASP1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all Caspase 1 (CASP1) products
- Caspase 1 (CASP1)
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- LQTRVLNKEE MEKVKRENAT VMDKTRALID SVIPKGAQAC QICITYICEE
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-CASP1 Antibody(ARP58983_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- Caspase 1 (CASP1)
- 别名
- ICE Peptide, IL1BC Peptide, P45 Peptide, Il1bc Peptide, Ice Peptide, CASP1 Peptide, CG5370 Peptide, DCP-1 Peptide, DCP1 Peptide, Dcp1 Peptide, Dmel\\CG5370 Peptide, ccp1 Peptide, dcp-1 Peptide, dcp1 Peptide, l(2)01862 Peptide, l(2)02132 Peptide, caspase 1 Peptide, caspase 1, apoptosis-related cysteine peptidase Peptide, caspase 4, apoptosis-related cysteine peptidase Peptide, Death caspase-1 Peptide, caspase-1 Peptide, caspase Peptide, caspase recruitment domain-containing protein 16 Peptide, caspase 4 Peptide, CASP1 Peptide, Casp1 Peptide, CASP4 Peptide, Dcp-1 Peptide, Caspase1 Peptide, LOC5564196 Peptide, LOC451519 Peptide
- 背景
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This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms.
Alias Symbols: ICE, IL1BC, P45
Protein Interaction Partner: AR,ATN1,ATXN3,HTT,PSEN1,AR,ATN1,ATXN3,BCAP31,BCL2L1,BID,CARD16,CARD17,CARD8,CASP1,CASP14,CAST,CDK11A,CDK11B,EGFR,HTT,IL18,IL1B,LMNA,MAPT,NEDD4,NFE2L2,NLRC4,NLRP1,NOD1,PAK1,PARK2,PARP1,PLA2G4A,PSEN1,PSEN2,PYCARD,RIPK2,TFAP2A,BCAP31,CARD8,CASP1,CASP10,CASP1
Protein Size: 383 - 分子量
- 10 kDa
- 基因ID
- 834
- NCBI登录号
- NM_001223, NP_001214
- UniProt
- P29466
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