ATP/GTP Binding Protein 1 (AGTPBP1) (C-Term) Peptide
AGTPBP1
适用: 人, 小鼠
宿主: 合成
BP, WB
产品编号 ABIN1541167
发货至:
中国
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Contact Info
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Quick Overview for ATP/GTP Binding Protein 1 (AGTPBP1) (C-Term) Peptide (ABIN1541167)
抗原
AGTPBP1
(ATP/GTP Binding Protein 1 (AGTPBP1))
宿主
人, 小鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- GMQPLMYSVQ EALNARPWWI RMGTDICYYK NHFSRSSVAA GGQKGKSYYT
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产品特性
- This is a synthetic peptide designed for use in combination with anti-Agtpbp1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AGTPBP1 (ATP/GTP Binding Protein 1 (AGTPBP1))
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背景
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Agtpbp1 is a metallocarboxypeptidase that mediates deglutamylation of target proteins. It catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. It also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Agtpbp1 acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. Deglutamylation plays a key role in cerebellar Purkinje cell differentiation, accumulation of tubulin polyglutamylation causing neurodegeneration.
Alias Symbols: 1700020N17Rik, 2310001G17Rik, 2900054O13Rik, 4930445M19Rik, 5730402G09Rik, BB114605, CCP1, Nna1, mKIAA1035, nmf243, pcd
Protein Size: 1160 -
分子量
- 128 kDa
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基因ID
- 67269
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NCBI登录号
- NM_023328, NP_075817
抗原
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